| 货号 | 规格 | 价格 | 上海 | 北京 | 珠海 | 重庆 | 武汉 | 购买数量 |
|---|---|---|---|---|---|---|---|---|
S82221-2mg买3赠1 |
99.70% | ￥272.00 |
5 | - | - | - | - |
|
S82221-5mg买3赠1 |
99.70% | ￥340.00 |
6 | - | - | - | - |
|
S82221-10mg买3赠1 |
99.70% | ￥580.00 |
6 | - | - | - | - |
|
S82221-25mg买3赠1 |
99.70% | ￥970.00 |
6 | - | - | - | - |
|
S82221-50mg促销 |
99.70% | ￥1450.00 ￥1160.00 |
4 | - | - | - | - |
|
S82221-100mg促销 |
≥98% | ￥2130.00 ￥1700.00 |
货期：2-3天 | - | - | - | - |
|
| 产品描述： | AG126 is a tyrosine kinase inhibitor, can inhibit the phosphorylation of ERK1 and ERK2 at 25-50 μM. AG126 can be used in meiosis, mitosis, and postmitotic research | ||||||||||||||||||||
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| 靶点： | ERK2;ERK; COX | ||||||||||||||||||||
| 体内研究： | AG 126 (intraperitoneal injection; 1-10 mg/kg; 1 h and 6 h after Zymosan treatment) treatment attenuates the degree of multiple organ failure (MOF) associated with Zymosan-induced peritonitis in the rat | ||||||||||||||||||||
| 参考文献： | 1. Cuzzocrea S, et al. The tyrosine kinase inhibitor tyrphostin AG126 reduces the development of acute and chronic inflammation. Am J Pathol. 2000 Jul;157(1):145-58. 2. Garg TK, et al. Oxidative stress causes ERK phosphorylation and cell death in cultured retinal pigment epithelium: prevention of cell death by AG126 and 15-deoxy-delta 12, 14-PGJ2. BMC Ophthalmol. 2003 Mar 21;3:5. 3. Dugo L, et al. The tyrosine kinase inhibitor tyrphostin AG 126 reduces the multiple organ failure induced by zymosan in the rat. Intensive Care Med. 2002 Jun;28(6):775-88. 4. Bullard LE, et al. Role for extracellular signal-responsive kinase-1 and -2 in retinal angiogenesis. Invest Ophthalmol Vis Sci. 2003 Apr;44(4):1722-31. | ||||||||||||||||||||
| 溶解性： | DMSO : 100 mg/mL (464.75 mM; Need ultrasonic and warming) | ||||||||||||||||||||
| 保存条件： | -20℃ | ||||||||||||||||||||
| 配置溶液浓度参考： |
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| 注意： | 部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。 |
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