| 货号 | 规格 | 价格 | 上海 | 北京 | 珠海 | 重庆 | 武汉 | 购买数量 |
|---|---|---|---|---|---|---|---|---|
S82283-10mg |
≥99% | ￥430.00 |
货期：3-5天 | - | - | - | - |
|
S82283-50mg |
≥99% | ￥1030.00 |
货期：3-5天 | - | - | - | - |
|
| 产品描述： | Olprinone (Loprinone) Hydrochloride is a potent phosphodiesterase (PDE) 3 inhibitor, with IC50s of 150, 100, 0.35 and 14 μM for PDE1, PDE2, PDE3 and PDE4, respectively. Olprinone Hydrochloride is used for the research of heart failure due to its positive inotropic and vasodilative effects. Anti-inflammatory activity | ||||||||||||||||||||
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| 靶点： | Phosphodiesterase (PDE) | ||||||||||||||||||||
| 体内研究： | Olprinone (Loprinone) Hydrochloride (0.2 mg/kg; i.p.) modulates the inflammation associated with myocardial ischemia-reperfusion injury in rats | ||||||||||||||||||||
| 参考文献： | 1. Sugioka M, et al. Identification and characterization of isoenzymes of cyclic nucleotide phosphodiesterase in human kidney and heart, and the effects of new cardiotonic agents on these isoenzymes. Naunyn Schmiedebergs Arch Pharmacol. 1994;350(3):284-293. 2. Di Paola R, et al. Olprinone, a PDE3 inhibitor, modulates the inflammation associated with myocardial ischemia-reperfusion injury in rats. Eur J Pharmacol. 2011;650(2-3):612-620. | ||||||||||||||||||||
| 溶解性： | Soluble in H2O | ||||||||||||||||||||
| 保存条件： | 2-8℃ | ||||||||||||||||||||
| 配置溶液浓度参考： |
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| 注意： | 部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。 |
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