| 产品描述： | LY2979165 is the alanine proagent of 2812223, a selective and potent orthosteric mGlu2 receptor agonist |
| 靶点： |
mGlu2 Receptor;GluR |
| 体内研究： |
LY2979165 attenuated the ketamine-evoked BOLD phMRI signal in vivo |
| 参考文献： |
1. Juliet McColm , et al. Evaluation of Single and Multiple Doses of a Novel mGlu2 Agonist, a Potential Antipsychotic Therapy, in Healthy Subjects. Br J Clin Pharmacol. 2017 Aug;83(8):1654-1667. 2. Mitul A Mehta, et al. Group II metabotropic glutamate receptor agonist prodrugs LY2979165 and LY2140023 attenuate the functional imaging response to ketamine in healthy subjects. Psychopharmacology (Berl). 2018 Jul;235(7):1875-1886. |
| 溶解性： |
Soluble in DMSO、H2O |
| 保存条件： |
-20℃ |
| 配置溶液浓度参考： |
|
1mg |
5mg |
10mg |
| 1 mM |
2.561 ml |
12.807 ml |
25.614 ml |
| 5 mM |
0.512 ml |
2.561 ml |
5.123 ml |
| 10 mM |
0.256 ml |
1.281 ml |
2.561 ml |
| 50 mM |
0.051 ml |
0.256 ml |
0.512 ml |
|
| 注意： |
部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。 |
上海工商
危险品化学品经营许可证（不带存储）
营业执照(三证合一)
北京