| 产品描述: | FASN-IN-4 is a potent inhibitor of fatty acid synthase (FASN) with an IC50 of 10 nM (WO2012064642A1, compound 29). FASN-IN-4 also inhibits SARS-CoV-2 with an EC50 of 18.6 nM |
| 靶点: |
IC50: 10 nM (FASN) EC50: 18.6 nM (SARS-CoV-2);Others |
| 体外研究: |
The FASN inhibitor, FASN-IN-4 inhibits SARS-CoV-2 replication, and has the potential for COVID-19 research |
| 参考文献: |
1. Nicholas D. Adams, et al. Fatty acid synthase inhibitors. WO2012064642A1. 2. Junjun Chu, et al. Pharmacological inhibition of fatty acid synthesis blocks SARS-CoV-2 replication. Nat Metab. 2021 Nov;3(11):1466-1475. |
| 溶解性: |
10 mM in DMSO |
| 保存条件: |
-20℃ |
| 配置溶液浓度参考: |
|
1mg |
5mg |
10mg |
| 1 mM |
2.094 ml |
10.47 ml |
20.939 ml |
| 5 mM |
0.419 ml |
2.094 ml |
4.188 ml |
| 10 mM |
0.209 ml |
1.047 ml |
2.094 ml |
| 50 mM |
0.042 ml |
0.209 ml |
0.419 ml |
|
| 注意: |
部分产品我司仅能提供部分信息,我司不保证所提供信息的权威性,仅供客户参考交流研究之用。 |