| 货号 | 规格 | 价格 | 上海 | 北京 | 珠海 | 重庆 | 武汉 | 购买数量 |
|---|---|---|---|---|---|---|---|---|
S83129-5mg促销 |
96.00% | ￥1620.00 ￥1290.00 |
6 | - | - | - | - |
|
S83129-10mg促销 |
96.00% | ￥2330.00 ￥1860.00 |
6 | - | - | - | - |
|
S83129-25mg促销 |
96.00% | ￥3670.00 ￥2930.00 |
6 | - | - | - | - |
|
| 产品描述： | Ca2+ channel agonist 1 is an agonist of N-type Ca2+ channel and an inhibitor of Cdk2, with EC50s of 14.23 μM and 3.34 μM, respectively, and is used as a potential treatment for motor nerve terminal dysfunction | ||||||||||||||||||||
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| 靶点： | CDK2:3.34 μM (EC50);N-type calcium channel:14.23 μM (EC50);CalciumChannel; CDK | ||||||||||||||||||||
| 体外研究： | Ca2+ channel agonist 1 (Compound 13d) is an agonist of N-type Ca2+ channel and an inhibitor of Cdk2, with EC50s of 14.23 μM and 3.34 μM, respectively. Ca2+ channel agonist 1 exhibits a ca. 2-fold increased agonism and a 22-fold decreased cdk2 kinase activity versus the standard, (R)-roscovitine | ||||||||||||||||||||
| 参考文献： | 1. Liang M, et al. Synthesis and biological evaluation of a selective N- and p/q-type calcium channel agonist. ACS Med Chem Lett. 2012 Oct 1;3(12):985-990. | ||||||||||||||||||||
| 溶解性： | Soluble in DMSO | ||||||||||||||||||||
| 保存条件： | -20℃ | ||||||||||||||||||||
| 配置溶液浓度参考： |
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| 注意： | 部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。 |
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