Entecavir

99.90%

Entecavir

质检下载产品说明书核磁下载 SDS 产品使用指南

品牌：源叶(MedMol)

产品编号：S83243 一键复制产品信息

CAS号：142217-69-4

分子式：C₁₂H₁₅N₅O₃

分子量：277.283

别名：恩替卡韦;9-(4-羟基-3-羟甲基-2-亚甲基环戊-1-基)鸟嘌呤;2-氨基-9-((1S,3R,4S)-4-羟基-3-(羟甲基)-2-甲烯基环戊基)-3H-嘌呤-6(9H)-酮;恩替卡韦-D2;Entecavir;Entecavir Baraclude;2-Amino-1,9-Dihydro-9-[(1S,3R,4S)-4-Hydroxy-3-(Hydroxymethyl)-2-Methyle

货号	规格	价格	上海	北京	珠海	重庆	武汉
S83243-5mg	99.90%	￥380.00 S83243-5mg ￥380.00 现货	6 6	-	-	-	-
S83243-10mg	99.90%	￥580.00 S83243-10mg ￥580.00 现货	10 10	-	-	-	-
S83243-50mg	99.90%	￥1590.00 S83243-50mg ￥1590.00 现货	5 5	-	-	-	-
S83243-100mg	≥98%	￥2250.00 S83243-100mg ￥2250.00 2-3天	0 货期：2-3天	-	-	-	-

大包装询价收藏产品

加入购物车

产品介绍参考文献(2篇) 质检证书(COA) 摩尔浓度计算器相关产品

产品描述：

Entecavir is a guanosine nucleoside analogue used in the treatment of chronic hepatitis B virus (HBV) infection. Entecavir therapy can be associated with flares of the underlying hepatitis B during or after therapy, but has not been linked to cases of clinically apparent liver injury.

靶点：

HBV

体内研究：

Daily oral treatment with BMS-200475 at doses ranging from 0.02 to 0.5 mg/kg of body weight for 1 to 3 months is effective in reducing the level of woodchuck hepatitis virus (WHV) viremia in chronically infected woodchucks

细胞实验：

BMS 200475 is prepared in phosphate-buffered saline (PBS) and diluted with appropriate medium containing 2% fetal bovine serum. HepG2 2.2.15 cells are plated at a density of 5×105 cells per well on 12-well Biocoat collagen-coated plates and are maintained in a confluent state for 2 to 3 days before being overlaid with 1 mL of medium spiked with BMS 200475. Quantification of HBV was performed on day 10

参考文献：

1. Xie B, Sun D, Du Y, et al. A two-step lineage reprogramming strategy to generate functionally competent human hepatocytes from fibroblasts[J]. Cell research. 2019: 1. 2. Sham, H., Kempf, D., Molla, A., Marsh, K., Kumar, G., & Chen, C. et al. (1998). ABT-378, a Highly Potent Inhibitor of the Human Immunodeficiency Virus Protease. Antimicrobial Agents And Chemotherapy, 42(12), 3218-3224. doi: 10.1128/aac.42.12.3218

溶解性：

Soluble in DMSO

保存条件：

-20℃

配置溶液浓度参考：

	1mg	5mg	10mg
1 mM	3.606 ml	18.032 ml	36.064 ml
5 mM	0.721 ml	3.606 ml	7.213 ml
10 mM	0.361 ml	1.803 ml	3.606 ml
50 mM	0.072 ml	0.361 ml	0.721 ml