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NMS-859

    
95.40%

NMS-859

源叶(MedMol)
S83380 一键复制产品信息
1449236-96-7
C15H12ClN3O3S
349.7921
货号 规格 价格 上海 北京 珠海 重庆 武汉 购买数量
S83380-2mg促销
95.40%

¥1050.00 ¥840.00

5 - - - -
S83380-5mg促销
95.40%

¥1620.00 ¥1290.00

6 - - - -
S83380-10mg促销
95.40%

¥2330.00 ¥1860.00

6 - - - -
S83380-25mg促销
95.40%

¥3710.00 ¥2960.00

5 - - - -
产品介绍 参考文献 质检证书(COA) 摩尔浓度计算器 相关产品
产品描述: NMS-859 is a potent, covalent VCP (p97) inhibitor, with IC50s of 0.37 and 0.36 μM for wild-type VCP in the presence of 60 μM and 1 mM ATP in cells, respectively.
靶点: IC50: 360 nM (Cellular p97, 1 mM ATP), 370 nM (Cellular p97, 60 μM ATP);Others
体外研究: NMS-859 is a potent VCP inhibitor, with IC50s of 0.37 and 0.36 μM for wild-type VCP in the presence of 60 μM and 1 mM ATP in cells, respectively. NMS-859 shows very weak inhibitory activity against VCPC522T. NMS-859 also suppresses the proliferation of cells, with IC50s of 3.5 μM and 3.0 μM in HCT116 and HeLa cell lines, respectively
参考文献: 1. Magnaghi P, et al. Covalent and allosteric inhibitors of the ATPase VCP/p97 induce cancer cell death. Nat Chem Biol. 2013 Sep;9(9):548-56.
溶解性: soluble  in  DMSO
保存条件: -20℃
配置溶液浓度参考:
1mg 5mg 10mg
1 mM 2.859 ml 14.294 ml 28.588 ml
5 mM 0.572 ml 2.859 ml 5.718 ml
10 mM 0.286 ml 1.429 ml 2.859 ml
50 mM 0.057 ml 0.286 ml 0.572 ml
注意: 部分产品我司仅能提供部分信息,我司不保证所提供信息的权威性,仅供客户参考交流研究之用。

参考文献

质检证书(COA)

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摩尔浓度计算器

质量 (mg) = 浓度 (mM) x 体积 (mL) x 分子摩尔量 (g/mol)

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