货号	规格	价格	上海	北京	珠海	重庆	武汉
S83495-5mg	≥98%	￥660.00 S83495-5mg ￥660.00 3-5天	0 货期：3-5天	-	-	-	-
S83495-10mg	≥98%	￥900.00 S83495-10mg ￥900.00 3-5天	0 货期：3-5天	-	-	-	-
S83495-25mg	≥98%	￥1890.00 S83495-25mg ￥1890.00 3-5天	0 货期：3-5天	-	-	-	-
S83495-50mg	≥98%	￥3250.00 S83495-50mg ￥3250.00 3-5天	0 货期：3-5天	-	-	-	-

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产品描述：

(S)-MCPG ((+)-MCPG) is a potent group I/II metabotropic glutamate receptor (mGluRs) antagonist and the active isomer of (RS)-MCPG (HY-100371). (S)-MCPG can be used for the study of the function of mGluRs in spatial learning

靶点：

mGluR;Others

体内研究：

MCPG (intraventricular injection; 20 μg) treated rat are slower to learn the task and takes longer to reach the platform than vehicle injected animals. On days 2 and 3, MCPG rats has a significant longer escape latency and the measure of search error is significantly longer on each of the first 3 days. On day 4, MCPG-treated animals reaches the same level of performance as control animals in Morris water maze

参考文献：

1. Bernadett Boda, et al. Reversal of activity-mediated spine dynamics and learning impairment in a mouse model of Fragile X syndrome. Eur J Neurosci. 2014 Apr;39(7):1130-7. 2. F Bordi, et al. Effects of the metabotropic glutamate receptor antagonist MCPG on spatial and context-specific learning. Neuropharmacology. 1996;35(11):1557-65.

溶解性：

Soluble in DMSO

保存条件：

配置溶液浓度参考：

	1mg	5mg	10mg
1 mM	4.78 ml	23.901 ml	47.801 ml
5 mM	0.956 ml	4.78 ml	9.56 ml
10 mM	0.478 ml	2.39 ml	4.78 ml
50 mM	0.096 ml	0.478 ml	0.956 ml

注意：

部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。

参考文献

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摩尔浓度计算器

质量 (mg) = 浓度 (mM) x 体积 (mL) x 分子摩尔量 (g/mol)

质量

浓度

体积

分子摩尔量

计算重置

(+)-Alpha-Methyl-4-Carboxyphenylglycine