| 货号 | 规格 | 价格 | 上海 | 北京 | 珠海 | 重庆 | 武汉 | 购买数量 |
|---|---|---|---|---|---|---|---|---|
S83773-1mg买3赠1 |
99.90% | ￥212.00 |
8 | - | - | - | - |
|
S83773-2mg买3赠1 |
99.90% | ￥365.00 |
8 | - | - | - | - |
|
S83773-5mg买3赠1 |
99.90% | ￥590.00 |
8 | - | - | - | - |
|
S83773-10mg买3赠1 |
99.90% | ￥750.00 |
10 | - | - | - | - |
|
S83773-25mg促销 |
99.90% | ￥1500.00 ￥1200.00 |
5 | - | - | - | - |
|
S83773-50mg促销 |
99.90% | ￥2450.00 ￥1960.00 |
4 | - | - | - | - |
|
S83773-100mg促销 |
≥98% | ￥3820.00 ￥3050.00 |
1 | - | - | - | - |
|
| 产品描述： | YM-90709 is a novel IL-5 inhibitor which selectively blocks the binding of IL-5 to the IL-5 receptor (IL-5R).YM-90709 potently inhibits the binding of [125I]-IL-5 to IL-5R on human peripheral eosinophils and eosinophilic HL-60 clone 15 cells with IC50 values of 1.0 and 0.57 μM | ||||||||||||||||||||
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| 靶点： | IL-5;ILReceptor; Interleukin | ||||||||||||||||||||
| 体内研究： | YM-90709 (0.01-10 mg/kg; intravenous injection, 72 hours, Inbred female Brown-Norway (BN) rats) results in the inhibition of antigen-induced infiltration of eosinophils and lymphocytes, but not neutrophils or monocytes, into the bronchoalveolar lavage fluid (BALF) of Brown-Norway (BN) rats | ||||||||||||||||||||
| 参考文献： | 1. Morokata T, et al. Characterization of YM-90709 as a novel antagonist which inhibits the binding of interleukin-5 to interleukin-5 receptor. Int Immunopharmacol. 2002 Nov;2(12):1693-702. 2. Morokata T, et al. Effect of a novel interleukin-5 receptor antagonist, YM-90709, on antigen-induced eosinophil infiltration into the airway of BDF1 mice. Immunol Lett. 2005 Apr 15;98(1):161-5. | ||||||||||||||||||||
| 溶解性： | DMSO : 62.5 mg/mL (173.89 mM; Need ultrasonic) | ||||||||||||||||||||
| 保存条件： | RT | ||||||||||||||||||||
| 配置溶液浓度参考： |
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| 注意： | 部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。 |
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