货号	规格	价格	上海	北京	珠海	重庆	武汉	购买数量
S83999-10mg	≥98%	￥990.00 S83999-10mg ￥990.00 3-5天	0 货期：3-5天	-	-	-	-
S83999-50mg	≥98%	￥3170.00 S83999-50mg ￥3170.00 3-5天	0 货期：3-5天	-	-	-	-

大包装询价收藏产品

加入购物车

到货通知，提交手机号入库后将短信通知。

产品描述：

SDZ 220-581 Ammonium salt is an orally active, potent, competitive NMDA receptor antagonist with pKi value of 7.7

靶点：

pKi: 7.7 (NMDA receptor);Others

体内研究：

SDZ 220-581 (3.2-32 mg/kg; oral administration; for 24 hours; male OF-l mice) treatment dose-dependently protects mice against maximal electroshock seizures (MES). The time-course of protection by SDZ 220-581 is characterized by a rapid onset and long duration of action. Animal Model: Male OF-l mice (18-26 g) Dosage: 3.2 mg/kg, 10 mg/kg, 32 mg/kg Administration: Oral administration; for 24 hours Result: Dose-dependently protected mice against maximal electroshock seizures (MES) upon oral administration.

参考文献：

1. Urwyler S, et al. Biphenyl-derivatives of 2-amino-7-phosphono-heptanoic acid, a novel class of potent competitive N-methyl-D-aspartate receptor antagonists--II. Pharmacological characterization in vivo. Neuropharmacology. 1996 Jun;35(6):655-69. 2. Gilmour G, et al. In vitro characterisation of the novel positive allosteric modulators of the mGlu₅ receptor, LSN2463359 and LSN2814617, and their effects on sleep architecture and operant responding in the rat. Neuropharmacology. 2013 Jan;64:224-39.

溶解性：

DMSO: < 3.9 mg/mL

保存条件：

-20℃

配置溶液浓度参考：

	1mg	5mg	10mg
1 mM	2.586 ml	12.928 ml	25.855 ml
5 mM	0.517 ml	2.586 ml	5.171 ml
10 mM	0.259 ml	1.293 ml	2.586 ml
50 mM	0.052 ml	0.259 ml	0.517 ml

注意：

部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。

参考文献

质检证书(COA)

输入产品批号：

如何获取质检证书(COA)?

请输入货号和一个与之匹配的批号。
例如:
批号：JS298415 货号：S20001-25g
在货品标签上如何找到货号和批号?

摩尔浓度计算器

质量 (mg) = 浓度 (mM) x 体积 (mL) x 分子摩尔量 (g/mol)

质量

浓度

体积

分子摩尔量

计算重置

SDZ 220-581 (Ammonium salt)