货号	规格	价格	上海	北京	珠海	重庆	武汉
S84136-5mg促销	98%	￥454.00 ￥408.00 S84136-5mg ￥408.00 3-5天	0 货期：3-5天	-	-	-	-
S84136-10mg促销	98%	￥700.00 ￥630.00 S84136-10mg ￥630.00 现货	8 8	-	-	-	-
S84136-25mg促销	98%	￥1250.00 ￥1130.00 S84136-25mg ￥1130.00 现货	3 3	-	-	-	-
S84136-100mg促销	98%	￥3700.00 ￥3330.00 S84136-100mg ￥3330.00 现货	3 3	-	-	-	-

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产品描述：

Endomorphin 1 is a high affinity and selective agonist of the μ-opioid receptor and displays reasonable affinities for kappa3 binding sites (Ki: 20~30 nM).

靶点：

Opioid Receptor;OpioidReceptor

体内研究：

Both Endomorphin 1 and Endomorphin 2 are potent analgesics with peak effects seen at 10 and 15 min, respectively. All subsequent studies are performed at peak effect. Both compounds are fully active supraspinally and spinally, with no indication of ceiling effects. Both Endomorphin 1 and Endomorphin 2 display a profile similar to morphine. Neither compound has analgesic activity in CXBK mice at a dose that produced over 70% analgesia in control CD-1 mice.

动物实验：

Groups of mice are treated i.c.v. with Endomorphin 1 (12 μg) or Endomorphin 2 (3 μg) 15 min before a 0.5-cc charcoal meal (2.5% gum tragacanth,10% activated charcoal in water). The mice are killed 30 min later and the distance the charcoal traveled is measured.

参考文献：

1. Goldberg IE, et al. Pharmacological characterization of endomorphin-1 and endomorphin-2 in mouse brain. J Pharmacol Exp Ther. 1998 Aug;286(2):1007-13.

溶解性：

Soluble in H2O

保存条件：

-20℃

配置溶液浓度参考：

	1mg	5mg	10mg
1 mM	1.637 ml	8.187 ml	16.375 ml
5 mM	0.327 ml	1.637 ml	3.275 ml
10 mM	0.164 ml	0.819 ml	1.637 ml
50 mM	0.033 ml	0.164 ml	0.327 ml

注意：

部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。

参考文献

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摩尔浓度计算器

质量 (mg) = 浓度 (mM) x 体积 (mL) x 分子摩尔量 (g/mol)

质量

浓度

体积

分子摩尔量

计算重置

内吗啡肽 1

Endomorphin 1

参考文献

质检证书(COA)

如何获取质检证书(COA)?

摩尔浓度计算器

质量 (mg) = 浓度 (mM) x 体积 (mL) x 分子摩尔量 (g/mol)