货号	规格	价格	上海	北京	珠海	重庆	武汉
S84400-5mg	≥99%	￥980.00 S84400-5mg ￥980.00 3-5天	0 货期：3-5天	-	-	-	-
S84400-10mg	≥99%	￥1740.00 S84400-10mg ￥1740.00 3-5天	0 货期：3-5天	-	-	-	-
S84400-25mg	≥99%	￥3890.00 S84400-25mg ￥3890.00 3-5天	0 货期：3-5天	-	-	-	-
S84400-50mg	≥99%	￥6210.00 S84400-50mg ￥6210.00 3-5天	0 货期：3-5天	-	-	-	-

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产品描述：

Eniporide hydrochloride (EMD-96785 hydrochloride) is a potent Na+/H+ exchange inhibitor.

靶点：

Sodium Channel

体外研究：

There is no significant effects of the Na+/H+ exchange inhibitor eniporide on cardiac performance and high energy phosphate content in healthy pig hearts subjected to ischemia/reperfusion induced by crystalloid cardioplegic arrest

体内研究：

In stage 1, the administration of 100 mg and 150 mg eniporide results in smaller infarct sizes, especially in the angioplasty group. In contrast, in stage 2 there is no difference in the enzymatic infarct size between the three groups. Overall there is no effect of eniporide on clinical outcome (death, cardiogenic shock, heart failure, life-threatening arrhythmias). However, there is a significant reduction of the incidence of heart failure in patients reperfused late (>4 h)

参考文献：

1. Klass O, et al. Effect of the Na+/H+ exchange inhibitor eniporide on cardiac performance and myocardial high energy phosphates in pigs subjected to cardioplegic arrest. Ann Thorac Surg. 2004 Feb;77(2):658-63. 2. Zeymer U, et al. The Na(+)/H(+) exchange inhibitor eniporide as an adjunct to early reperfusion therapy for acute myocardial infarction. Results of the evaluation of the safety and cardioprotective effects of eniporide in acute myocardial infarction (ESCAMI) trial. J Am Coll Cardiol. 2001 Nov 15;38(6):1644-50.

溶解性：

Soluble in DMSO、H2O

保存条件：

-20℃

配置溶液浓度参考：

	1mg	5mg	10mg
1 mM	2.802 ml	14.012 ml	28.025 ml
5 mM	0.56 ml	2.802 ml	5.605 ml
10 mM	0.28 ml	1.401 ml	2.802 ml
50 mM	0.056 ml	0.28 ml	0.56 ml

注意：

部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。

参考文献

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摩尔浓度计算器

质量 (mg) = 浓度 (mM) x 体积 (mL) x 分子摩尔量 (g/mol)

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