| 货号 | 规格 | 价格 | 上海 | 北京 | 珠海 | 重庆 | 武汉 | 购买数量 |
|---|---|---|---|---|---|---|---|---|
S84445-5mg促销 |
≥95% | ￥570.00 ￥450.00 |
10 | - | - | - | - |
|
S84445-10mg促销 |
≥95% | ￥794.00 ￥630.00 |
6 | - | - | - | - |
|
S84445-25mg促销 |
≥95% | ￥1600.00 ￥1270.00 |
1 | - | - | - | - |
|
S84445-50mg促销 |
≥95% | ￥3560.00 ￥2840.00 |
货期：3-5天 | - | - | - | - |
|
S84445-100mg促销 |
≥95% | ￥4000.00 ￥3190.00 |
1 | - | - | - | - |
|
| 产品描述： | Etifoxine, a non-benzodiazepine GABAergic compound, is a positive allosteric modulator of α1β2γ2 and α1β3γ2 subunit-containing GABAA receptors. Etifoxine reveals anxiolytic and anticonvulsant properties in rodents | ||||||||||||||||||||
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| 靶点： | GABA Receptor;Others | ||||||||||||||||||||
| 体内研究： | Etifoxine competitively inhibits [35S]TBPS binding with micromolar potency in rat brain. Etifoxine (3.125-50 mg/kg) exhibits more pronounced anxiolytic and anticonvulsant effects in the BALB/cByJ mice compared to the C57BL/6J mice | ||||||||||||||||||||
| 参考文献： | 1. Marc Verleye, et al. Effects of etifoxine on ligand binding to GABA(A) receptors in rodents. Neurosci Res. 2002 Oct;44(2):167-72. 2. Alain Hamon, et al. The modulatory effects of the anxiolytic etifoxine on GABA(A) receptors are mediated by the beta subunit. Neuropharmacology. 2003 Sep;45(3):293-303. 3. Marc Verleye, et al. Differential effects of etifoxine on anxiety-like behaviour and convulsions in BALB/cByJ and C57BL/6J mice: any relation to overexpression of central GABAA receptor beta2 subunits? Eur Neuropsychopharmacol. 2011 Jun;21(6):457-70. | ||||||||||||||||||||
| 溶解性： | Soluble in DMSO | ||||||||||||||||||||
| 保存条件： | -20℃ | ||||||||||||||||||||
| 配置溶液浓度参考： |
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| 注意： | 部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。 |
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