| 产品描述: | Oxyclozanide is an orally active salicylanilide anthelmintic agent that mainly acts by uncoupling oxidative phosphorylation in flukes. Oxyclozanide shows good anti-adenovirus, anti-biofilm, antifungal, and antibacterial activity |
| 靶点: |
Parasite;Antibiotic; Parasite |
| 体内研究: |
Oxyclozanide (15 mg/kg (羊),10 mg/kg (牛);口服) 在羊和牛中显示出抗寄生虫的效果。 Oxyclozanide (1500-5000 mg/kg;口服,一次) 在大鼠急性毒性试验中出现多种中毒症状 |
| 参考文献: |
1. Georgiev B, Gruev A. Efektivnost na levamizole i oxyclozanide sreshtu paramfistomatozata po ovtsete i govedata [Effectiveness of levamisole and oxyclozanide in paramphistomiasis in sheep and cattle]. Vet Med Nauki. 1979;16(3):45-51. 2. Wang W, et al. Acute and Subacute Toxicity Assessment of Oxyclozanide in Wistar Rats. Front Vet Sci. 2019 Sep 6;6:294. 3. Levinson MR, et al. The in vitro antibacterial activity of the anthelmintic drug oxyclozanide against common small animal bacterial pathogens. Vet Dermatol. 2019 Aug;30(4):314-e87. |
| 溶解性: |
DMSO : 100 mg/mL (249.09 mM; Need ultrasonic) |
| 保存条件: |
2-8℃ |
| 配置溶液浓度参考: |
|
1mg |
5mg |
10mg |
| 1 mM |
2.491 ml |
12.455 ml |
24.909 ml |
| 5 mM |
0.498 ml |
2.491 ml |
4.982 ml |
| 10 mM |
0.249 ml |
1.245 ml |
2.491 ml |
| 50 mM |
0.05 ml |
0.249 ml |
0.498 ml |
|
| 注意: |
部分产品我司仅能提供部分信息,我司不保证所提供信息的权威性,仅供客户参考交流研究之用。 |