| 货号 | 规格 | 价格 | 上海 | 北京 | 珠海 | 重庆 | 武汉 | 购买数量 |
|---|---|---|---|---|---|---|---|---|
S85008-5mg买3赠1 |
99.00% | ￥272.00 |
5 | - | - | - | - |
|
S85008-10mg买3赠1 |
99.00% | ￥350.00 |
5 | - | - | - | - |
|
S85008-25mg买3赠1 |
99.00% | ￥430.00 |
7 | - | - | - | - |
|
S85008-100mg买3赠1 |
99.00% | ￥1130.00 |
2 | - | - | - | - |
|
| 产品描述： | Nucleozin, a potent inhibitor of influenza A virus infection, induces the formation of nucleoprotein (NP) aggregates and antagonizes its nuclear accumulation, leading to cessation of viral replication. Nucleozin impedes influenza A virus replication in vitro with a nanomolar EC50 | ||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 靶点： | Influenza Virus;InfluenzaVirus | ||||||||||||||||||||
| 体外研究： | Nucleozin inhibits infection of MDCK cells by the viruses influenza A/WSN/33, H3N2 and Vietnam/1194/04 (H5N1) with an EC50 of 0.069 μM, 0.16 μM and 0.33 μM in plaque reduction assay (PRA) , respectively, severely suppresses viral growth at 0.1 μM and totally inhibites virus production at 1 μM in multicycle growth assays | ||||||||||||||||||||
| 体内研究： | Nucleozin protectes mice challenged with lethal doses of avian influenza A H5N1 | ||||||||||||||||||||
| 参考文献： | 1. Kao RY, et al. Identification of influenza A nucleoprotein as an antiviral target. Nat Biotechnol. 2010;28(6):600-605. | ||||||||||||||||||||
| 溶解性： | Soluble in DMSO | ||||||||||||||||||||
| 保存条件： | -20℃ | ||||||||||||||||||||
| 配置溶液浓度参考： |
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| 注意： | 部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。 |
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