货号	规格	价格	上海	北京	珠海	重庆	武汉
S85865-5mg	99%	￥320.00 S85865-5mg ￥320.00 2-3天	0 货期：2-3天	-	-	-	-
S85865-10mg	99%	￥408.00 S85865-10mg ￥408.00 2-3天	0 货期：2-3天	-	-	-	-
S85865-50mg买3赠1	99%	￥512.00 S85865-50mg ￥512.00 2-3天（买3赠1）	0 货期：2-3天	-	-	-	-
S85865-100mg买3赠1	99%	￥728.00 S85865-100mg ￥728.00 2-3天（买3赠1）	0 货期：2-3天	-	-	-	-

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产品描述：

Angiotensin II 5-valine is an agonist of angiotensin receptor.

靶点：

Angiotensin receptor;RAAS

体内研究：

By day 12, systolic blood pressure (SBP) increases significantly in Angiotensin II 5-valine infused rats (197±7 mm Hg). As shown, the development of hypertension in ANG II infused rats is prevented by losartan treatment. Blood and kidney samples are harvested, subjected to HPLC to separate Angiotensin II 5-valine (exogenous) from Ile5-ANG II (endogenous) and the fractions are measured by radioimmunoassay. In the Angiotensin II 5-valine infused rats treated with losartan, total plasma ANG II levels are elevated to a greater extent than in rats not treated with losartan (289±20 v 119±14 fmol/mL). However, losartan markedly decrease by 88% the enhancement of intrarenal Val5-ANG II content that occurred in the rats infused with Val5-ANG II alone

参考文献：

1. Zou LX et al. Renal uptake of circulating angiotensin II in Val5-angiotensin II infused rats is mediated by AT1 receptor. Am J Hypertens. 1998 May;11(5):570-8.

溶解性：

Soluble in H2O

保存条件：

-20°C

配置溶液浓度参考：

	1mg	5mg	10mg
1 mM	0.969 ml	4.844 ml	9.689 ml
5 mM	0.194 ml	0.969 ml	1.938 ml
10 mM	0.097 ml	0.484 ml	0.969 ml
50 mM	0.019 ml	0.097 ml	0.194 ml

注意：

部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。

参考文献

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摩尔浓度计算器

质量 (mg) = 浓度 (mM) x 体积 (mL) x 分子摩尔量 (g/mol)

质量

浓度

体积

分子摩尔量

计算重置

[Val5]-Angiotensin II