| 货号 | 规格 | 价格 | 上海 | 北京 | 珠海 | 重庆 | 武汉 | 购买数量 |
|---|---|---|---|---|---|---|---|---|
S85921-5mg买3赠1 |
99.90% | ￥204.00 |
4 | - | - | - | - |
|
S85921-10mg买3赠1 |
99.90% | ￥285.00 |
5 | - | - | - | - |
|
S85921-25mg买3赠1 |
99.90% | ￥450.00 |
3 | - | - | - | - |
|
S85921-50mg买3赠1 |
99.90% | ￥670.00 |
2 | - | - | - | - |
|
S85921-100mg |
≥98% | ￥1000.00 |
货期：2-3天 | - | - | - | - |
|
S85921-200mg |
≥98% | ￥1500.00 |
货期：2-3天 | - | - | - | - |
|
| 产品描述： | OAC2 is an Oct4 activator which activates expression through the Oct4 gene promoter; enhances reprogramming efficiency by increasing the rate of production of induced pluripotent stem cells (iPSCs) from embryonic fibroblasts; an analog of OAC1. |
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| 靶点： | OCT | ||||||||||||||||||||
| 细胞实验： | The Oct4-luc or Nanog-luc cells are treated with compound OAC1 or its structural analogs OAC2, OAC3 at 1 μM concentration or at indicated concentrations. Other compounds used include 2 μM BIO, 2 μM BIX, 2 μM 5'-azacytidine, 25 μg/mL Vitamin C, 10 nM Am580, 5 μM tranylcypromine, and 0.5 mM valporic acid. Luciferase reporter assays are performed 24 h after compound treatment or at indicated time points. For Topflash reporter assays, 0.2 μg β-catenin–responsive Topflash reporter gene plasmid is introduced into CV1 cells using trasfection. Compounds are added 6 h after transfection. Luciferase activity is measured 48 h after compound treatment using the Glo Luciferase Assay System | ||||||||||||||||||||
| 参考文献： | 1Li W, et al. Identification of Oct4-activating compounds that enhance reprogramming efficiency. Proc Natl Acad Sci U S A. 2012 Dec 18;109(51):20853-8. 2.Okuyama T, et al. Structural and mechanistic insights into nuclear transport and delivery of the critical pluripotency factor Oct4 to DNA. J Biomol Struct Dyn. 2017 Feb 6:1-50 | ||||||||||||||||||||
| 溶解性： | Soluble in DMSO | ||||||||||||||||||||
| 保存条件： | 2-8℃ | ||||||||||||||||||||
| 配置溶液浓度参考： |
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| 注意： | 部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。 |
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