货号	规格	价格	上海	北京	珠海	重庆	武汉
S86096-5mg	≥99%	￥738.00 S86096-5mg ￥738.00 现货	9 9	-	-	-	-
S86096-10mg	≥99%	￥1180.00 S86096-10mg ￥1180.00 现货	10 10	-	-	-	-
S86096-25mg	≥99%	￥2060.00 S86096-25mg ￥2060.00 现货	8 8	-	-	-	-
S86096-50mg	≥99%	￥3290.00 S86096-50mg ￥3290.00 现货	5 5	-	-	-	-
S86096-100mg	≥99%	￥4600.00 S86096-100mg ￥4600.00 现货	5 5	-	-	-	-

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产品描述：

Etimizol(Ethymisole; Antiffine; Ethylnorantifein) was shown to relieve amnesia effectively in the origin of which there is the hypoxic component (hypobaric hypoxia, actinomycin D, mechanical injury of the brain).

体内研究：

The time interval between administration ofetimizol (3 mg/kg) and the onset of learning varied between 0.5 and 3 h in the several series. Etimizol (Ethymisole) did not facilitate the learning in rats whatever the time of administration and biological modality of reinforcement. After administration of Etimizol (Ethymisole) at doses of 10 or 1 mg/loop mean residence time of etimizol in the loop was 20.1 and 7.6 min, respectively, with mean standard deviation being 3.1 and 0.8, respectively. Extracellular application of 5--10 mM/L Etimizol (Ethymisole) exerted a specific effect on the giant neurons of the Coretus corneus isolated nervous system: action potential duration increased significantly, speed of development of its descending phase decreased, as well as the trace hyperpolarization amplitude

参考文献：

1. Borisova GIu. Effect of etimizol on instrumental learning in rats. Biull Eksp Biol Med. 1985 Jun;99(6):705-6. 2. Trnovec T, et al. Etimizol absorption from the small intestine in dogs: the dependence on dosage. Biull Eksp Biol Med. 1986 Dec;102(12):729-30. 3. Vislobokov AI, et al. Elektrophysiological parameters of mollusk neurons under the influence of etimizol. Fiziol Zh SSSR Im I M Sechenova. 1975 Jun;61(6):917-24.

溶解性：

Soluble in DMSO

保存条件：

-20℃

配置溶液浓度参考：

	1mg	5mg	10mg
1 mM	4.757 ml	23.783 ml	47.567 ml
5 mM	0.951 ml	4.757 ml	9.513 ml
10 mM	0.476 ml	2.378 ml	4.757 ml
50 mM	0.095 ml	0.476 ml	0.951 ml

注意：

部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。

参考文献

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