iCRT-14

    
98%

iCRT-14

源叶(MedMol)
S86185 一键复制产品信息
677331-12-3
C21H17N3O2S
375.44
货号 产品规格 价格(RMB) 库存(上海) 北京 武汉 南京 购买数量
S86185-2mg 98% ¥220.00 5 - - -
S86185-5mg 98% ¥320.00 9 - - -
S86185-10mg 98% ¥480.00 6 - - -
S86185-25mg 98% ¥720.00 6 - - -
S86185-50mg 98% ¥1230.00 预计交期:2-3天 - - -
产品介绍 参考文献 质检证书(COA) 摩尔浓度计算器 相关产品

产品介绍

iCRT 14 is a novel potent inhibitor of β-catenin-responsive transcription (CRT), with IC50 of 40.3 nM against Wnt responsive STF16 luciferase.

产品描述: iCRT 14 is a novel potent inhibitor of β-catenin-responsive transcription (CRT), with IC50 of 40.3 nM against Wnt responsive STF16 luciferase.
靶点: IC50: 40.3 nM (Wnt responsive STF16 luciferase);Wnt/beta-catenin
体内研究: iCRT14 (50 mg/kg, i.p.) markedly decreases CycD1, proliferation of the tumors in HCT116 xenografts
参考文献: 1. Gonsalves FC, et al. An RNAi-based chemical genetic screen identifies three small-molecule inhibitors of the Wnt/wingless signaling pathway. Proc Natl Acad Sci USA. 2011 Apr 12;108(15):5954-63. 2. Bilir B, et al. Wnt signaling blockage inhibits cell proliferation and migration, and induces apoptosis in triple-negative breast cancer cells. J Transl Med. 2013 Nov 4;11:280.
溶解性: Soluble  in  DMSO
保存条件: 2-8℃
配置溶液浓度参考:
1mg 5mg 10mg
1 mM 2.664 ml 13.318 ml 26.635 ml
5 mM 0.533 ml 2.664 ml 5.327 ml
10 mM 0.266 ml 1.332 ml 2.664 ml
50 mM 0.053 ml 0.266 ml 0.533 ml
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参考文献

质检证书(COA)

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摩尔浓度计算器

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