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Piroctone olamine

    
99.40%

Piroctone olamine

源叶(MedMol)
S86217 一键复制产品信息
68890-66-4
C14H23NO2 · C2H7NO
298.42
MFCD01690792
吡罗克酮乙醇胺盐;羟吡酮;1-羟基-4-甲基-6-(2,4,4-三甲基戊基)-2(1H)-吡啶酮 乙醇胺盐
货号 规格 价格 上海 北京 珠海 重庆 武汉 购买数量
S86217-50mg买3赠1
99.40%

¥240.00

>10 - - - -
S86217-100mg买3赠1
99.40%

¥370.00

6 - - - -
产品介绍 参考文献 质检证书(COA) 摩尔浓度计算器 相关产品
产品描述: Piroctone olamine is a pyridine derivate. It is known to have a fungicidal effect.
靶点: Antifungal;Antibiotic;Antifungal
体内研究: This work aimed to evaluate the antifungal activity of Piroctone olamine in the treatment of intra-abdominal candidiasis in an experimental model using Swiss mice. The treatment with Piroctone olamine (0.5 mg/kg) is performed 72 h after infection by intraperitoneal administration. For comparison, a group of animals (n=6) is treated with Amphotericin B (0.5 mg/kg). The mycological diagnosis is made by collecting the liver, spleen and kidneys. Data regarding the fungal growth and mortality are analyzed statistically by Student’s t test and analysis of variance, with level of significance set at P<0.05. The difference in fungal growth scoring between the control group and the treatment groups (Piroctone olamine and Amphotericin B) is statistically significant (P<0.05)
参考文献: 1. Youn HJ, et al. Efficacy and Safety of Cream Containing Climbazole/Piroctone Olamine for Facial Seborrheic Dermatitis: A Single-Center, Open-Label Split-Face Clinical Study. Ann Dermatol. 2016 Dec;28(6):733-739. 2. do Couto FM, et al. Antifungal activity of the piroctone olamine in experimental intra-abdominal candidiasis. Springerplus. 2016 Apr 16;5:468.
溶解性: Soluble  in  DMSO、H2O
保存条件: 2-8℃
配置溶液浓度参考:
1mg 5mg 10mg
1 mM 3.351 ml 16.755 ml 33.51 ml
5 mM 0.67 ml 3.351 ml 6.702 ml
10 mM 0.335 ml 1.675 ml 3.351 ml
50 mM 0.067 ml 0.335 ml 0.67 ml
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参考文献

质检证书(COA)

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摩尔浓度计算器

质量 (mg) = 浓度 (mM) x 体积 (mL) x 分子摩尔量 (g/mol)

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