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DGAT-3

    
99.70%

DGAT-3

源叶(MedMol)
S86263 一键复制产品信息
701232-20-4
C22H26N4O3
394.472
反式-4-[4-(4-氨基-7,7-二甲基-7H-嘧啶并[4,5-B][1,4]噁唑-6-基)苯基]-环己基乙酰胺;反式-4-[4-(4-氨基-7,7-二甲基-7H-嘧啶并[4,5-B][1,4]恶嗪-6-基)苯基]环己烷乙酸;DGAT-3;Cyclohexaneacetic acid, 4-[4-(4-amino-7,7-dimethyl-7H-pyrimido[4,5-b][1,4]oxazi
货号 规格 价格 上海 北京 珠海 重庆 武汉 购买数量
S86263-2mg买3赠1
99.70%

¥272.00

3 - - - -
S86263-5mg买3赠1
99.70%

¥476.00

1 - - - -
S86263-10mg买3赠1
99.70%

¥850.00

3 - - - -
S86263-25mg买3赠1
99.70%

¥1590.00

6 - - - -
S86263-50mg买3赠1
99.70%

¥2900.00

4 - - - -
S86263-100mg
≥98%

¥5000.00

货期:2-3天 - - - -
产品介绍 参考文献 质检证书(COA) 摩尔浓度计算器 相关产品
产品描述: T863 is an orally active, selective and potent DGAT1 (Acyl-CoA:diacylglycerol acyltransferase 1) inhibitor that interacts with the acyl-CoA binding site of DGAT1, and inhibits triacylglycerol synthesis in cells.
靶点: Acyltransferase;Acyltransferase;Transferase
参考文献: 1. Cao J, et al. Targeting Acyl-CoA:diacylglycerol acyltransferase 1 (DGAT1) with small molecule inhibitors for the treatment of metabolic diseases. J Biol Chem. 2011 Dec 2;286(48):41838-51. 2. Dow RL, et al. Design and synthesis of potent, orally-active DGAT-1 inhibitors containing a dioxino[2,3-d]pyrimidine core. Bioorg Med Chem Lett. 2011 Oct 15;21(20):6122-5. 3. Qian Y, et al. Discovery of orally active carboxylic acid derivatives of 2-phenyl-5-trifluoromethyloxazole-4-carboxamide as potent diacylglycerol acyltransferase-1 inhibitors for the potential treatment of obesity and diabetes. J Med Chem. 2011 Apr 14;54
溶解性: Soluble  in  DMSO
保存条件: 2-8℃
配置溶液浓度参考:
1mg 5mg 10mg
1 mM 2.535 ml 12.675 ml 25.35 ml
5 mM 0.507 ml 2.535 ml 5.07 ml
10 mM 0.254 ml 1.268 ml 2.535 ml
50 mM 0.051 ml 0.254 ml 0.507 ml
注意: 部分产品我司仅能提供部分信息,我司不保证所提供信息的权威性,仅供客户参考交流研究之用。

参考文献

质检证书(COA)

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批号:JS298415 货号:S20001-25g
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摩尔浓度计算器

质量 (mg) = 浓度 (mM) x 体积 (mL) x 分子摩尔量 (g/mol)

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