| 货号 | 规格 | 价格 | 上海 | 北京 | 珠海 | 重庆 | 武汉 | 购买数量 |
|---|---|---|---|---|---|---|---|---|
S86599-1mg买3赠1 |
98.30% | ￥200.00 |
9 | - | - | - | - |
|
S86599-5mg买3赠1 |
98.30% | ￥490.00 |
6 | - | - | - | - |
|
S86599-10mg买3赠1 |
98.30% | ￥730.00 |
6 | - | - | - | - |
|
S86599-25mg买3赠1 |
98.30% | ￥990.00 |
6 | - | - | - | - |
|
S86599-50mg促销 |
≥98% | ￥1750.00 ￥1400.00 |
货期：2-3天 | - | - | - | - |
|
S86599-100mg促销 |
≥98% | ￥2970.00 ￥2370.00 |
货期：2-3天 | - | - | - | - |
|
| 产品描述： | Vesnarinone (OPC-8212) is an orally active phosphodiesterase 3 (PDE3) inhibitor. Vesnarinone can increase in calcium flux and decrease in potassium flux. Vesnarinone shows dose-dependent positive inotropic activity. Vesnarinone can be used in heart failure research | ||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 靶点： | Phosphodiesterase (PDE);PotassiumChannel;CalciumChannel;PDE | ||||||||||||||||||||
| 体内研究： | Vesnarinone (oral gavage; 300 mg/kg; once daily; 6 w) binds covalently to rat liver in vivo | ||||||||||||||||||||
| 参考文献： | 1. A Matsumori, et al. Vesnarinone, a new inotropic agent, inhibits cytokine production by stimulated human blood from patients with heart failure. Circulation. 1994 Mar;89(3):955-8. 2. E Cavusoglu, et al. Vesnarinone: a new inotropic agent for treating congestive heart failure. J Card Fail. 1995 Jun;1(3):249-57. 3. K Yoneda, et al. Induction of cyclin-dependent kinase inhibitor p21 in vesnarinone-induced differentiation of squamous cell carcinoma cells. Cancer Lett. 1998 Nov 13;133(1):35-45. 4. Iain Gardner, et al. A comparison of the covalent binding of clozapine, procainamide, and vesnarinone to human neutrophils in vitro and rat tissues in vitro and in vivo. Chem Res Toxicol. 2005 Sep;18(9):1384-94. | ||||||||||||||||||||
| 溶解性： | Soluble in DMSO | ||||||||||||||||||||
| 保存条件： | 2-8℃ | ||||||||||||||||||||
| 配置溶液浓度参考： |
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| 注意： | 部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。 |
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