| 货号 | 规格 | 价格 | 上海 | 北京 | 珠海 | 重庆 | 武汉 | 购买数量 |
|---|---|---|---|---|---|---|---|---|
S86942-2mg买3赠1 |
99.04% | ￥212.00 |
5 | - | - | - | - |
|
S86942-5mg买3赠1 |
99.04% | ￥374.00 |
5 | - | - | - | - |
|
S86942-10mg买3赠1 |
99.04% | ￥526.00 |
6 | - | - | - | - |
|
S86942-25mg买3赠1 |
99.04% | ￥930.00 |
6 | - | - | - | - |
|
S86942-50mg买3赠1 |
99.04% | ￥1380.00 |
5 | - | - | - | - |
|
S86942-100mg买3赠1 |
99.04% | ￥2020.00 |
5 | - | - | - | - |
|
S86942-200mg买3赠1 |
≥99% | ￥3500.00 |
货期：2-3天 | - | - | - | - |
|
| 产品描述： | SC66 is an Akt inhibitor, reduces cell viability in a dose- and time-dependent manner, inhibits colony formation and induces apoptosis in hepatocellular carcinoma (HCC) cells. | ||||||||||||||||||||
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| 靶点： | Akt;Apoptosis;Akt | ||||||||||||||||||||
| 体内研究： | To demonstrate the effectiveness in vivo of SC66 on HCC, a mouse xenograft tumor model of Hep3B cells is used. When tumors became palpable, at a size of about 150 mm3, mice are randomized into three groups of 6 animals each. The treated group receive SC66 at 15 and 25 mg/kg twice a week via i.p. injection, while the untreated group receive the vehicle alone. Treatment with 25 mg/Kg SC66 significantly reduces tumor volume to 37% on day 17 when compared with tumors of the untreated group | ||||||||||||||||||||
| 参考文献： | 1. Cusimano A, et al. Cytotoxic activity of the novel small molecule AKT inhibitor SC66 in hepatocellular carcinoma cells. Oncotarget. 2015 Jan 30;6(3):1707-22. | ||||||||||||||||||||
| 溶解性： | Soluble in DMSO | ||||||||||||||||||||
| 保存条件： | 2-8℃ | ||||||||||||||||||||
| 配置溶液浓度参考： |
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| 注意： | 部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。 |
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