| 货号 | 规格 | 价格 | 上海 | 北京 | 珠海 | 重庆 | 武汉 | 购买数量 |
|---|---|---|---|---|---|---|---|---|
S87463-1mg |
99.80% | ￥220.00 |
9 | - | - | - | - |
|
S87463-2mg |
99.80% | ￥300.00 |
10 | - | - | - | - |
|
S87463-5mg |
99.80% | ￥370.00 |
>10 | - | - | - | - |
|
S87463-10mg |
99.80% | ￥680.00 |
10 | - | - | - | - |
|
S87463-25mg |
99.80% | ￥760.00 |
8 | - | - | - | - |
|
S87463-50mg |
≥99% | ￥1390.00 |
货期：2-3天 | - | - | - | - |
|
| 产品描述： | Acebilustat (CTX-4430) is a leukotriene A4 hydrolase inhibitor, used for an oral antiinflammatory agent. | ||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 靶点： | Aminopeptidase;Aminopeptidase; LTR | ||||||||||||||||||||
| 体外研究： | Acebilustat (CTX-4430) is a leukotriene A4 hydrolase inhibitor, which is safe and well tolerated in phase 1 trial. Acebilustat is an antiinflammatory drug in development for the treatment of CF and other diseases. It is a potent inhibitor of the enzyme leukotriene A4 hydrolase (LTA4H), which catalyzes the rate-limiting step in the formation of leukotriene B4 (LTB4), a potent chemoattractant and activator of inflammatory immune cells including neutrophils | ||||||||||||||||||||
| 参考文献： | 1. Elborn JS, et al. Phase 1 Studies of Acebilustat: Biomarker Response and Safety in Patients with Cystic Fibrosis. Clin Transl Sci. 2016 Nov 2 2. Elborn JS, et al. Phase I Studies of Acebilustat: Pharmacokinetics, Pharmacodynamics, Food Effect, and CYP3A Induction. Clin Transl Sci. 2016 Oct 28. | ||||||||||||||||||||
| 溶解性： | Soluble in DMSO | ||||||||||||||||||||
| 保存条件： | -20℃ | ||||||||||||||||||||
| 配置溶液浓度参考： |
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| 注意： | 部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。 |
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