品牌：源叶(MedMol)

产品编号：S87466 一键复制产品信息

CAS号：94424-50-7

分子式：C₂₀H₃₄ClN₃O₃S

分子量：432.02

别名：盐酸喹高莱;(3S,4aS,10aR)-3-(二乙基氨磺酰氨基)-6-羟基-1-丙基-3,4,4a,5,10,10a-六氢-2H-苯并[g]喹啉盐酸盐;QUINAGOLIDE HYDROCHLORIDE;(3S,4aS,10aR)-3-(Diethylsulfamoylamino)-6-hydroxy-1-propyl-3,4,4a,5,10,10a-hexahydro-2H-benzo[g]qu

货号	规格	价格	上海	北京	珠海	重庆	武汉	购买数量
S87466-5mg	≥99%	￥2800.00 S87466-5mg ￥2800.00 2-3天	0 货期：2-3天	-	-	-	-
S87466-10mg	≥99%	￥4100.00 S87466-10mg ￥4100.00 2-3天	0 货期：2-3天	-	-	-	-

大包装询价收藏产品

加入购物车

到货通知，提交手机号入库后将短信通知。

产品描述：

Quinagolide hydrochloride (CV205-502 hydrochloride) is a selective and orally active dopamine D2 receptor agonist. Quinagolide hydrochloride is an inhibitor of prolactin. Quinagolide hydrochloride down-regulates AKT levels and its phosphorylation. Quinagolide hydrochloride shows antitumor effects, it can be used for the research of cancer

靶点：

Dopamine Receptor;Akt

体内研究：

Quinagolide hydrochloride (0.03-0.6 mg/kg; s.c. once daily for 2 month) effectively inhibits tumor growth in vivo. Animal Model: Female Wistar-Furth rats bearing SMtTW tumors Dosage: 0.03-0.6 mg/kg Administration: Subcutaneous injection; 0.03-0.6 mg/kg once daily for 2 month Result: Induced normalization of plasma PRL levels in all animals, reduced the tumor size compared with the control group at a dose of 0.3 mg/kg. Showed maximal inhibitory effects on PRL secretion and tumor growth at a dose of 0.3 mg/kg.

参考文献：

1. Trouillas J, et al. Inhibitory effects of the dopamine agonists quinagolide (CV 205-502) and bromocriptine on prolactin secretion and growth of SMtTW pituitary tumors in the rat. Endocrinology. 1994 Jan;134(1):401-10. 2. Iampietro C, et al. Quinagolide Treatment Reduces Invasive and Angiogenic Properties of Endometrial Mesenchymal Stromal Cells. Int J Mol Sci. 2022 Feb 4;23(3):1775.

溶解性：

Soluble in DMSO

保存条件：

2-8℃

配置溶液浓度参考：

	1mg	5mg	10mg
1 mM	2.315 ml	11.574 ml	23.147 ml
5 mM	0.463 ml	2.315 ml	4.629 ml
10 mM	0.231 ml	1.157 ml	2.315 ml
50 mM	0.046 ml	0.231 ml	0.463 ml

注意：

部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。

参考文献

质检证书(COA)

输入产品批号：

如何获取质检证书(COA)?

请输入货号和一个与之匹配的批号。
例如:
批号：JS298415 货号：S20001-25g
在货品标签上如何找到货号和批号?

摩尔浓度计算器

质量 (mg) = 浓度 (mM) x 体积 (mL) x 分子摩尔量 (g/mol)

质量

浓度

体积

分子摩尔量

计算重置