| 货号 | 规格 | 价格 | 上海 | 北京 | 珠海 | 重庆 | 武汉 | 购买数量 |
|---|---|---|---|---|---|---|---|---|
S87747-10mg买3赠1 |
99.80% | ￥400.00 |
3 | - | - | - | - |
|
S87747-25mg买3赠1 |
99.80% | ￥720.00 |
2 | - | - | - | - |
|
S87747-100mg |
≥98% | ￥1440.00 |
货期：2-3天 | - | - | - | - |
|
S87747-250mg |
≥98% | ￥2800.00 |
货期：2-3天 | - | - | - | - |
|
| 产品描述： | MD 69276 (Toloxatone) is a reversible monoamine oxidase A (MAOA) inhibitor. | ||||||||||||||||||||
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| 靶点： | MAO;Monoamine Oxidase;MAO; MonoamineOxidase | ||||||||||||||||||||
| 体内研究： | The maximum increase in systolic blood pressure produced by four single oral doses of tyramine administered during a meal and ranging from 100 mg to 800 mg was compared during repeated (3 to 5 days) administration of placebo, 200 mg toloxatone three times a day and 400 mg toloxatone three times a day in a single-blind, three-period crossover study. Toloxatone by itself had no significant influence on blood pressure. During administration of toloxatone, no significant increase in tyramine-induced increase in systolic blood pressure was observed for tyramine doses of 200 mg or less that are consistently higher than those associated with normal food intake | ||||||||||||||||||||
| 参考文献： | 1. FMoureau, et al. A reversible monoamine oxidase inhibitor, toloxatone: spectrophotometric and molecular orbital studies of the interaction with flavin adenine dinucleotide (FAD). European Journal of Medicinal Chemistry. 1994, 29(4):269-277. 2. Provost JC, et al. Pharmacokinetic and pharmacodynamic interaction between toloxatone, a new reversible monoamine oxidase-A inhibitor, and oral tyramine in healthy subjects. Clin Pharmacol Ther. 1992 Oct;52(4):384-93. | ||||||||||||||||||||
| 溶解性： | Soluble in DMSO | ||||||||||||||||||||
| 保存条件： | -20℃ | ||||||||||||||||||||
| 配置溶液浓度参考： |
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| 注意： | 部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。 |
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