| 货号 | 规格 | 价格 | 上海 | 北京 | 珠海 | 重庆 | 武汉 | 购买数量 |
|---|---|---|---|---|---|---|---|---|
S87762-5mg |
≥98% | ￥520.00 |
>10 | - | - | - | - |
|
S87762-10mg |
≥98% | ￥869.00 |
>10 | - | - | - | - |
|
S87762-25mg |
≥98% | ￥1730.00 |
10 | - | - | - | - |
|
S87762-50mg |
≥98% | ￥2190.00 |
5 | - | - | - | - |
|
S87762-100mg |
≥98% | ￥2920.00 |
2 | - | - | - | - |
|
| 产品描述： | GLX351322 is an inhibitor of NADPH oxidase 4 (Nox4), and inhibits hydrogen peroxide production from NOX4-overexpressing cells with an IC50 of 5 μM. | ||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 靶点： | IC50: 5 μ M (NOX4, cell assay), 40 μM (NOX2, cell assay);NADPH-oxidase; NADPH | ||||||||||||||||||||
| 体外研究： | GLX351322 is an inhibitor of NADPH oxidase 4, and inhibits hydrogen peroxide production from NOX4-overexpressing cells with an IC50 of 5 μM. GLX351322 shows weak activity against NOX2 in hPBMC cells (IC50, 40 μM). | ||||||||||||||||||||
| 体内研究： | GLX351322 (3.8 mg/kg/day, p.o.) ameliorates HFD-induced hyperglycemia in mice | ||||||||||||||||||||
| 参考文献： | 1. Anvari E, et al. The novel NADPH oxidase 4 inhibitor GLX351322 counteracts glucose intolerance in high-fat diet-treated C57BL/6 mice. Free Radic Res. 2015;49(11):1308-18. | ||||||||||||||||||||
| 溶解性： | Soluble in DMSO | ||||||||||||||||||||
| 保存条件： | -20℃ | ||||||||||||||||||||
| 配置溶液浓度参考： |
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| 注意： | 部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。 |
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北京