| 货号 | 规格 | 价格 | 上海 | 北京 | 珠海 | 重庆 | 武汉 | 购买数量 |
|---|---|---|---|---|---|---|---|---|
S87763-1mg买3赠1 |
99.90% | ￥140.00 |
9 | - | - | - | - |
|
S87763-5mg买3赠1 |
99.90% | ￥202.00 |
7 | - | - | - | - |
|
S87763-10mg买3赠1 |
99.90% | ￥380.00 |
9 | - | - | - | - |
|
S87763-50mg促销 |
99.90% | ￥1150.00 ￥920.00 |
6 | - | - | - | - |
|
S87763-100mg促销 |
≥98% | ￥2030.00 ￥1620.00 |
货期：2-3天 | - | - | - | - |
|
| 产品描述： | C-4 is a potential ATP-competitive inhibitor of mTOR. C-4 could inhibit cell growth and proliferation | ||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 靶点： | Autophagy;mTOR;mTOR; Autophagy | ||||||||||||||||||||
| 体外研究： | The addition of C-4 (mTOR inhibitor-1, 0~12.8 μg/ml) directly decreases the level of activated mTOR (p-mTORser2448) which is phosphorylated at Ser2448. The proliferation of A549 cells is strongly inhibited by C-4, and the inhibitory effect is time- and dose314 dependent. The IC50 of C-4 at 24 h is calculated as 3.176 μM. | ||||||||||||||||||||
| 参考文献： | 1. Liu J, et al. In Silico Discovery of a Small Molecule Suppressing Lung Carcinoma A549 Cells Proliferation and Inducing Autophagy via mTOR Pathway Inhibition. Mol Pharm. 2018 Nov 5;15(11):5427-5436. | ||||||||||||||||||||
| 溶解性： | Soluble in DMSO | ||||||||||||||||||||
| 保存条件： | -20℃ | ||||||||||||||||||||
| 配置溶液浓度参考： |
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| 注意： | 部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。 |
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