| 货号 | 规格 | 价格 | 上海 | 北京 | 珠海 | 重庆 | 武汉 | 购买数量 |
|---|---|---|---|---|---|---|---|---|
S87770-2mg买3赠1 |
99.90% | ￥350.00 |
5 | - | - | - | - |
|
S87770-5mg买3赠1 |
99.90% | ￥471.00 |
6 | - | - | - | - |
|
S87770-10mg买3赠1 |
99.90% | ￥800.00 |
6 | - | - | - | - |
|
S87770-25mg |
99.90% | ￥1318.00 |
6 | - | - | - | - |
|
S87770-50mg促销 |
≥98% | ￥2800.00 ￥2240.00 |
货期：2-3天 | - | - | - | - |
|
S87770-100mg促销 |
≥98% | ￥4390.00 ￥3510.00 |
货期：2-3天 | - | - | - | - |
|
| 产品描述： | Fabomotizole (CM346) is an anxiolytic agent. Fabomotizole produces anxiolytic and neuroprotective effects without any muscle relaxant actions. | ||||||||||||||||||||
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| 体外研究： | Afobazole's mechanism of action remains poorly defined however, with GABAergic, NGF and BDNF release promoting, MT1 receptor antagonism, MT3 receptor antagonism, and sigma agonism suggested as potential mechanisms. Afobazole was shown to inhibit MAO-A reversibly and there might be also some involvement with serotonin receptors. Afobazole has found little clinical use outside of Russia and has not been evaluated by the FDA. | ||||||||||||||||||||
| 体内研究： | Fabomotizole (15 mg/kg; ip; 单剂量) 可在蛋氨酸（3 g/kg，每天一次，共 7 天；胃内注射）模拟内皮功能障碍和异丙肾上腺素（20 μg/kg/min，持续 5 分钟；ip）诱导急性心内膜下缺血的麻醉大鼠模型中，降低内皮功能障碍和血管完整的大鼠中 ST 段压低。 | ||||||||||||||||||||
| 参考文献： | 1. Afobazole, From Wikipedia | ||||||||||||||||||||
| 溶解性： | Soluble in DMSO | ||||||||||||||||||||
| 保存条件： | -20℃ | ||||||||||||||||||||
| 配置溶液浓度参考： |
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| 注意： | 部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。 |
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