产品描述: | Cardiogenol C is a potent cell-permeable pyrimidine inducer which prompts the differentiation of ESCs into cardiomyocytes (EC50=100 nM). Cardiogenol C also acts cardiomyogenic on already lineage-committed progenitor cell types with a limited degree of plasticity. Cardiogenol C is a useful cardiomyogenic agent and can be used as a tool to improve cardiac repair by cell transplantation therapy in animal models |
靶点: |
EC50: 100 nM (differentiation of ESCs into cardiomyocytes);Wnt/beta-catenin |
参考文献: |
1. Wu X, et al. Small molecules that induce cardiomyogenesis in embryonic stem cells.J Am Chem Soc. 2004 Feb 18;126(6):1590-1. [Content Brief] 2. Mike AK, et al. Small molecule cardiogenol C upregulates cardiac markers and induces cardiac functional properties in lineage-committed progenitor cells. Cell Physiol Biochem. 2014;33(1):205-21. |
保存条件: |
-20℃ |
配置溶液浓度参考: |
|
1mg |
5mg |
10mg |
1 mM |
3.37 ml |
16.849 ml |
33.698 ml |
5 mM |
0.674 ml |
3.37 ml |
6.74 ml |
10 mM |
0.337 ml |
1.685 ml |
3.37 ml |
50 mM |
0.067 ml |
0.337 ml |
0.674 ml |
|
注意: |
部分产品我司仅能提供部分信息,我司不保证所提供信息的权威性,仅供客户参考交流研究之用。 |