| 货号 | 规格 | 价格 | 上海 | 北京 | 珠海 | 重庆 | 武汉 | 购买数量 |
|---|---|---|---|---|---|---|---|---|
S87852-5mg买3赠1 |
99.70% | ￥248.00 |
6 | - | - | - | - |
|
S87852-10mg买3赠1 |
99.70% | ￥410.00 |
7 | - | - | - | - |
|
S87852-25mg买3赠1 |
99.70% | ￥890.00 |
6 | - | - | - | - |
|
S87852-50mg促销 |
99.70% | ￥1480.00 ￥1180.00 |
4 | - | - | - | - |
|
S87852-100mg促销 |
≥98% | ￥2190.00 ￥1750.00 |
货期：2-3天 | - | - | - | - |
|
| 产品描述： | D3-βArr is a positive allosteric modulator for thyrotropin receptor (TSHR), which initiates translocation of β-Arr 1 (EC50: 11.6 μM) by direct TSHR activation | ||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 靶点： | TSH Receptor;TSHReceptor | ||||||||||||||||||||
| 体外研究： | D3-βArr stimulated β-Arr 1 translocation with an efficacy threefold greater than TSH. The EC50 for β-Arr 1 translocation by D3-βArr was 11.6 μM. D3-βArr (10 μM) increased the efficacy of TSH in the translocation of β-Arr 1 at a maximum of 5.1-fold over TSH alone | ||||||||||||||||||||
| 参考文献： | 1. Neumann S, et al. Discovery of a Positive Allosteric Modulator of the Thyrotropin Receptor: Potentiation of Thyrotropin-Mediated Preosteoblast Differentiation In Vitro. J Pharmacol Exp Ther. 2018 Jan;364(1):38-45. | ||||||||||||||||||||
| 溶解性： | Soluble in DMSO | ||||||||||||||||||||
| 保存条件： | 2-8℃ | ||||||||||||||||||||
| 配置溶液浓度参考： |
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| 注意： | 部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。 |
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