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化合物3A

    
98%

2-((3S,5R)-3,5-dimethylpiperazin-1-yl)benzo[4,5]imidazo[1,2-a][1,8]naphthyridine-6-carbonitrile

源叶(MedMol)
S87857 一键复制产品信息
1822358-25-7
C21H20N6
356.4237
Compound 3A
货号 规格 价格 上海 北京 珠海 重庆 武汉 购买数量
S87857-5mg促销
98%

¥890.00 ¥800.00

5 - - - -
S87857-10mg促销
98%

¥1500.00 ¥1350.00

5 - - - -
S87857-25mg促销
98%

¥2740.00 ¥2460.00

3 - - - -
S87857-50mg促销
98%

¥3400.00 ¥3060.00

1 - - - -
S87857-100mg促销
98%

¥4900.00 ¥4410.00

1 - - - -
产品介绍 参考文献 质检证书(COA) 摩尔浓度计算器 相关产品
产品描述: Compound 3A can effectively inhibit the transcription of RNA polymerase I in the A375 malignant melanoma cell line but has no effect on polymerase II.
靶点: DNA/RNA Synthesis;DNA/RNASynthesis
体内研究: Corynoxine promotes the formation of autophagosomes in the fat bodies of Drosophila. By inducing autophagy, Corynoxine promotes the clearance of wild-type and A53T α-syn in inducible PC12 cells. Corynoxine induces autophagy through the Akt/mTOR pathway as evidenced by the reduction in the levels of phospho-Akt, phospho-mTOR and phospho-p70 S6 Kinase. Corynoxine significantly decreased locomotor activity after oral administration to mice
参考文献: 1. Sakakibara I, et al. Effect on locomotion of indole alkaloids from the hooks of uncaria plants. Phytomedicine. 1999 Jul;6(3):163-8. 2. Chen L L , Song J X , Lu J H , et al. Corynoxine, a Natural Autophagy Enhancer, Promotes the Clearance of Alpha-Synuclein via Akt/mTOR Pathway[J]. Journal of Neuroimmune Pharmacology, 2014, 9(3):380-387.
溶解性: Soluble  in  DMSO
保存条件: -20℃
配置溶液浓度参考:
1mg 5mg 10mg
1 mM 2.806 ml 14.028 ml 28.056 ml
5 mM 0.561 ml 2.806 ml 5.611 ml
10 mM 0.281 ml 1.403 ml 2.806 ml
50 mM 0.056 ml 0.281 ml 0.561 ml
注意: 部分产品我司仅能提供部分信息,我司不保证所提供信息的权威性,仅供客户参考交流研究之用。

参考文献

质检证书(COA)

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摩尔浓度计算器

质量 (mg) = 浓度 (mM) x 体积 (mL) x 分子摩尔量 (g/mol)

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