| 货号 | 规格 | 价格 | 上海 | 北京 | 珠海 | 重庆 | 武汉 | 购买数量 |
|---|---|---|---|---|---|---|---|---|
S87857-5mg促销 |
98% | ￥890.00 ￥800.00 |
5 | - | - | - | - |
|
S87857-10mg促销 |
98% | ￥1500.00 ￥1350.00 |
5 | - | - | - | - |
|
S87857-25mg促销 |
98% | ￥2740.00 ￥2460.00 |
3 | - | - | - | - |
|
S87857-50mg促销 |
98% | ￥3400.00 ￥3060.00 |
1 | - | - | - | - |
|
S87857-100mg促销 |
98% | ￥4900.00 ￥4410.00 |
1 | - | - | - | - |
|
| 产品描述： | Compound 3A can effectively inhibit the transcription of RNA polymerase I in the A375 malignant melanoma cell line but has no effect on polymerase II. | ||||||||||||||||||||
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| 靶点： | DNA/RNA Synthesis;DNA/RNASynthesis | ||||||||||||||||||||
| 体内研究： | Corynoxine promotes the formation of autophagosomes in the fat bodies of Drosophila. By inducing autophagy, Corynoxine promotes the clearance of wild-type and A53T α-syn in inducible PC12 cells. Corynoxine induces autophagy through the Akt/mTOR pathway as evidenced by the reduction in the levels of phospho-Akt, phospho-mTOR and phospho-p70 S6 Kinase. Corynoxine significantly decreased locomotor activity after oral administration to mice | ||||||||||||||||||||
| 参考文献： | 1. Sakakibara I, et al. Effect on locomotion of indole alkaloids from the hooks of uncaria plants. Phytomedicine. 1999 Jul;6(3):163-8. 2. Chen L L , Song J X , Lu J H , et al. Corynoxine, a Natural Autophagy Enhancer, Promotes the Clearance of Alpha-Synuclein via Akt/mTOR Pathway[J]. Journal of Neuroimmune Pharmacology, 2014, 9(3):380-387. | ||||||||||||||||||||
| 溶解性： | Soluble in DMSO | ||||||||||||||||||||
| 保存条件： | -20℃ | ||||||||||||||||||||
| 配置溶液浓度参考： |
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| 注意： | 部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。 |
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