SKL2001 ≥98%
| 货号 | 规格 | 价格 | 上海 | 北京 | 珠海 | 重庆 | 武汉 | 购买数量 |
|---|---|---|---|---|---|---|---|---|
S88219-5mg |
≥98% | ￥260.00 |
货期：2-3天 | - | - | - | - |
|
S88219-10mg |
98.00% | ￥480.00 |
5 | - | - | - | - |
|
S88219-25mg |
98.00% | ￥960.00 |
7 | - | - | - | - |
|
S88219-50mg |
98.00% | ￥1760.00 |
4 | - | - | - | - |
|
S88219-100mg |
98.00% | ￥3360.00 |
3 | - | - | - | - |
|
| 产品描述： | SKL2001, an agonist of the Wnt/β-catenin pathway, can disrupt the Axin/β-catenin interaction. | ||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 靶点： | Wnt/beta-catenin | ||||||||||||||||||||
| 细胞实验： | The HEK293 reporter and control cell lines were established. The HEK293 reporter cells were inoculated into 384-well plates at 10 000 cells per well and grown for 24 h. Next, each compound in the chemical library (～270 000) was added to at a final concentration of 20 μM. After 15 h, the plates were assayed for firefly luciferase activity.(Only for Reference) | ||||||||||||||||||||
| 参考文献： | 1. Lu F, Sun X, Xu X, et al. SILAC-based proteomic profiling of the suppression of TGF-β1-induced lung fibroblast-to-myofibroblast differentiation by trehalose[J]. Toxicology and Applied Pharmacology. 2020, 391: 114916. 2. Lu F, Sun X, Xu X, et al. SILAC-based proteomic profiling of the suppression of TGF-β1-induced lung fibroblast-to-myofibroblast differentiation by trehalose[J]. Toxicology and Applied Pharmacology. 2020: 114916. 3. Gwak J, et al. Cell Res. 2012, 22(1):237-47. | ||||||||||||||||||||
| 溶解性： | Soluble in DMSO、Ethanol | ||||||||||||||||||||
| 保存条件： | -20℃ | ||||||||||||||||||||
| 配置溶液浓度参考： |
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| 注意： | 部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。 |
参考文献(2篇)
2. [IF=4.2] Xia Liang et al."Notch2 improves granulosa cell functions in premature ovarian failure by activating the Wnt2/β-catenin pathway."Journal of Ovarian Research.2025 Jul;18:169
1. [IF=2.1] He Haifa et al."Geniposide Inhibits Non-Small Cell Lung Cancer by Regulating Proliferation, Apoptosis, Invasion, Migration, Epithelial-Mesenchymal Transition, and Cancer Stem-Like Cell Property Via Wnt/β-Catenin Pathway."BIOCHEMICAL GENETICS.2025 Feb;:1-2
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