| 货号 | 规格 | 价格 | 上海 | 北京 | 珠海 | 重庆 | 武汉 | 购买数量 |
|---|---|---|---|---|---|---|---|---|
S88249-5mg促销 |
98% | ￥156.00 ￥140.00 |
10 | - | - | - | - |
|
S88249-10mg促销 |
98% | ￥208.00 ￥186.00 |
10 | 4 | - | - | - |
|
S88249-25mg促销 |
98% | ￥278.00 ￥250.00 |
10 | - | - | - | - |
|
S88249-50mg促销 |
98% | ￥552.00 ￥496.00 |
7 | - | - | - | - |
|
S88249-100mg促销 |
98% | ￥852.00 ￥766.00 |
3 | - | - | - | - |
|
S88249-250mg促销 |
98% | ￥1890.00 ￥1700.00 |
1 | - | - | - | - |
|
| 产品描述： | 5'-Fluoroindirubinoxime (5’-FIO, compound 13), an Indirubin (HY-N0117) derivative, is a potent FLT3 inhibitor, with an IC50 of 15 nM | ||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 靶点： | 15 nM (FLT3);FLT | ||||||||||||||||||||
| 体内研究： | 5'-Fluoroindirubinoxime (5’-FIO, 10 μmol/L/100 μL (~2.95 mg/mL) every other day beginning on day 6, S.C..) exhibits significant anti-tumor activity in rats. Animal Model: Rat tumor model based RK3E-ras cells. Dosage: S.C.. Administration: 10 μmol/L/100 μL (~2.95 mg/mL) every other day beginning on day 6. Result: Effectively inhibited tumor growth. | ||||||||||||||||||||
| 参考文献： | 1. Choi SJ, et al. Indirubin derivatives as potent FLT3 inhibitors with anti-proliferative activity of acute myeloid leukemic cells. Bioorg Med Chem Lett. 2010 Mar 15;20(6):2033-7. 2. Kim SA, et al. Antitumor activity of novel indirubin derivatives in rat tumor model. Clin Cancer Res. 2007 Jan 1;13(1):253-9. | ||||||||||||||||||||
| 溶解性： | Soluble in DMSO | ||||||||||||||||||||
| 保存条件： | -20℃ | ||||||||||||||||||||
| 配置溶液浓度参考： |
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| 注意： | 部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。 |
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