| 货号 | 规格 | 价格 | 上海 | 北京 | 珠海 | 重庆 | 武汉 | 购买数量 |
|---|---|---|---|---|---|---|---|---|
S88290-5mg买3赠1 |
98.10% | ￥200.00 |
5 | - | - | - | - |
|
S88290-10mg买3赠1 |
98.10% | ￥370.00 |
5 | - | - | - | - |
|
S88290-25mg买3赠1 |
98.10% | ￥650.00 |
4 | - | - | - | - |
|
S88290-50mg买3赠1 |
98.10% | ￥1150.00 |
6 | - | - | - | - |
|
S88290-100mg买3赠1 |
98.10% | ￥1960.00 |
6 | - | - | - | - |
|
| 产品描述： | Dorzagliatin (HMS5552), a dual-acting glucokinase (GK) activator, improves glycaemic control and pancreatic β-cell function in type 2 diabetes | ||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 靶点： | Glucokinas;Glucokinase | ||||||||||||||||||||
| 体内研究： | Dorzagliatin (低剂量 10 mg/kg，高剂量 30 mg/kg；胃内给药；每天上午 8:00，持续一个月) 对糖尿病大鼠的血糖水平产生降糖作用。 Animal Model: Male Sprague-Dawley (SD) rats (aged approximately 6–8 weeks and weighing 200-230 g) Dosage: Low-dose (10 mg/kg), and high-dose (30 mg/kg) Administration: Administered intragastrically (i.g.); daily (8:00 AM) for one month Result: Exerted a glucose-lowering effect on the glucose levels. | ||||||||||||||||||||
| 参考文献： | 1. Zhu XX, et al. Dorzagliatin (HMS5552), a novel dual-acting glucokinase activator, improves glycaemic control and pancreatic β-cell function in patients with type 2 diabetes: A 28-day treatment study using biomarker-guided patient selection. Diabetes Obes Metab. 2018 Sep;20(9):2113-2120. 2. Wang P, et al. Effects of a Novel Glucokinase Activator, HMS5552, on Glucose Metabolism in a Rat Model of Type 2 Diabetes Mellitus. J Diabetes Res. 2017;2017:5812607. | ||||||||||||||||||||
| 溶解性： | Soluble in DMSO | ||||||||||||||||||||
| 保存条件： | -20°C | ||||||||||||||||||||
| 配置溶液浓度参考： |
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| 注意： | 部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。 |
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