| 货号 | 规格 | 价格 | 上海 | 北京 | 珠海 | 重庆 | 武汉 | 购买数量 |
|---|---|---|---|---|---|---|---|---|
S88551-1mg买3赠1 |
98.10% | ￥120.00 |
9 | - | - | - | - |
|
S88551-5mg买3赠1 |
98.10% | ￥270.00 |
6 | - | - | - | - |
|
S88551-10mg促销 |
98.10% | ￥400.00 ￥320.00 |
5 | - | - | - | - |
|
S88551-25mg促销 |
98.10% | ￥820.00 ￥656.00 |
6 | - | - | - | - |
|
| 产品描述： | GET73 is a γ-hydroxybutyric acid (GHB) analog, a naturally occurring neurotransmitter. GET73 has anti-alcohol and anxiolytic properties. GET73 significantly affects glutamate transmission in the hippocampus | ||||||||||||||||||||
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| 靶点： | GluR | ||||||||||||||||||||
| 体内研究： | GET73 (5–50 mg/kg; i.g.) exerts an anxiolytic effect in Sprague-Dawley rats exposed to the elevated plus maze (EPM) test. Animal Model: Male SD rats (200-300 g and 300–350 g) Dosage: 5 mg/kg, 10 mg/kg, 25 mg/kg, 50 mg/kg Administration: Oral gavage Result: Exerted an anxiolytic effect in rats exposed to the elevated plus maze (EPM) test. | ||||||||||||||||||||
| 参考文献： | 1. Tomasini MC, et al. GET73 Prevents Ethanol-Induced Neurotoxicity in Primary Cultures of Rat Hippocampal Neurons. Alcohol Alcohol. 2016 Mar;51(2):128-35. 2. Ferraro L, et al. GET73 modulates rat hippocampal glutamate transmission: evidence for a functional interaction with mGluR5. Pharmacol Rep. 2011;63(6):1359-71. 3. Loche A, et al. Anti-Alcohol and Anxiolytic Properties of a New Chemical Entity, GET73. Front Psychiatry. 2012 Feb 14;3:8. | ||||||||||||||||||||
| 溶解性： | Soluble in DMSO | ||||||||||||||||||||
| 保存条件： | -20°C | ||||||||||||||||||||
| 配置溶液浓度参考： |
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| 注意： | 部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。 |
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