| 货号 | 规格 | 价格 | 上海 | 北京 | 珠海 | 重庆 | 武汉 | 购买数量 |
|---|---|---|---|---|---|---|---|---|
S88618-1mg |
≥98% | ￥40.00 |
10 | - | - | - | - |
|
S88618-5mg |
≥98% | ￥198.00 |
3 | - | - | - | - |
|
S88618-10mg |
≥98% | ￥390.00 |
3 | - | - | - | - |
|
S88618-25mg |
≥98% | ￥830.00 |
2 | - | - | - | - |
|
S88618-50mg |
≥98% | ￥1330.00 |
货期：2-3天 | - | - | - | - |
|
S88618-100mg |
≥98% | ￥2130.00 |
货期：2-4周 | - | - | - | - |
|
| 产品描述： | Bobcat339 is a potent and selective cytosine-based inhibitor of TET enzyme, with IC50s of 33 μM and 73 μM for TET1 and TET2, respectively. Bobcat339 is useful to the field of epigenetics and serves as a starting point for new therapeutics that target DNA methylation and gene transcription | ||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 靶点： | TET1:33 μM (IC50);TET2:73 μM (IC50);DNAMethyltransferase | ||||||||||||||||||||
| 体外研究： | Bobcat339 (10 μM; 24 hours) significantly reduces global 5hmC levels by inhibiting TET enzyme function in HT-22 cells | ||||||||||||||||||||
| 参考文献： | 1. Chua GNL, et, al. Cytosine-Based TET Enzyme Inhibitors. ACS Med Chem Lett. 2019 Jan 31; 10(2): 180-185. | ||||||||||||||||||||
| 溶解性： | Soluble in DMSO | ||||||||||||||||||||
| 保存条件： | -20°C | ||||||||||||||||||||
| 配置溶液浓度参考： |
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| 注意： | 部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。 |
上海工商
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北京