| 货号 | 规格 | 价格 | 上海 | 北京 | 珠海 | 重庆 | 武汉 | 购买数量 |
|---|---|---|---|---|---|---|---|---|
S88736-5mg买3赠1 |
98.30% | ￥610.00 |
5 | - | - | - | - |
|
S88736-10mg买3赠1 |
98.30% | ￥960.00 |
6 | - | - | - | - |
|
S88736-25mg买3赠1 |
98.30% | ￥1760.00 |
6 | - | - | - | - |
|
S88736-50mg买3赠1 |
98.30% | ￥2910.00 |
6 | - | - | - | - |
|
S88736-100mg买3赠1 |
98.30% | ￥4120.00 |
6 | - | - | - | - |
|
| 产品描述： | Verdiperstat (AZD3241) is a selective, irreversible and orally active myeloperoxidase (MPO) inhibitor, with an IC50 of 630 nM, and can be used in the research of neurodegenerative brain disorders. | ||||||||||||||||||||
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| 靶点： | IC50: 630 nM (Myeloperoxidase);GlutathionePeroxidase | ||||||||||||||||||||
| 体外研究： | Verdiperstat (AZD3241) is a myeloperoxidase (MPO) inhibitor, with an IC50 of 630 nM, and is used in the research of neurodegenerative brain disorders. Verdiperstat (AZD3241) selectively and irreversibly inhibits myeloperoxidase, and may involves reduction of oxidative stress leading to reduction of sustained neuroinflammation | ||||||||||||||||||||
| 参考文献： | 1. Johnström P, et al. Development of rapid multistep carbon-11 radiosynthesis of the myeloperoxidase inhibitor AZD3241 to assess brain exposure by PET microdosing. Nucl Med Biol. 2015 Jun;42(6):555-60. 2. Jucaite A, et al. Effect of the myeloperoxidase inhibitor AZD3241 on microglia: a PET study in Parkinson's disease. Brain. 2015 Sep;138(Pt 9):2687-700. | ||||||||||||||||||||
| 溶解性： | Soluble in DMSO | ||||||||||||||||||||
| 保存条件： | -20°C | ||||||||||||||||||||
| 配置溶液浓度参考： |
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| 注意： | 部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。 |
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