首页
订购/客服:400-666-5481

OGG1-IN-08

    
98.10%

3,4-DICHLORO-1-BENZOTHIOPHENE-2-CARBOHYDRAZIDE

源叶(MedMol)
S89018 一键复制产品信息
350997-39-6
C9H6Cl2N2OS
261.13
OGG1-IN-O8; OGG1 IN O8; OGG1INO8; OGG1 Inhibitor O8
货号 规格 价格 上海 北京 珠海 重庆 武汉 购买数量
S89018-5mg买3赠1
98.10%

¥348.00

6 - - - -
S89018-10mg买3赠1
98.10%

¥500.00

7 - - - -
S89018-25mg买3赠1
98.10%

¥850.00

5 - - - -
S89018-100mg促销
≥98%

¥2460.00 ¥1960.00

货期:2-3天 - - - -
产品介绍 参考文献 质检证书(COA) 摩尔浓度计算器 相关产品
产品描述: OGG1-IN-08 is a potent 8-oxoguanine DNA glycosylase-1 (OGG1) inhibitor with an IC50 value of 0.22 μM. OGG1-IN-08 decreases both the glycosylase and lyase activities of OGG1
靶点: IC50: 0.22 μM (OGG1)
体外研究: OGG1-IN-08 (50 μM) inhibits different DNA glycosylases activities, it inhibits nei endonuclease VIII-like 1 DNA glycosylase (NEIL1)(84.56%), endonuclease III-like (NTH1)(63.09%), and Fpg (91.74%), respectively. OGG1-IN-08 (10 μM) has a inhibitory OGG1 lyase activity on a substrate containing an AP site compared with the no inhibitor control. OGG1-IN-08 (10 μM) decreases the number of bases released into solution by OGG1 for both the 8-oxo-Gua and FapyGua compared with the no inhibitor
参考文献: 1. Nathan Donley,et al. Small Molecule Inhibitors of 8-Oxoguanine DNA Glycosylase-1 (OGG1). ACS Chem Biol. 2015 Oct 16;10(10):2334-43.
溶解性: Soluble  in  DMSO
保存条件: -20°C
配置溶液浓度参考:
1mg 5mg 10mg
1 mM 3.83 ml 19.148 ml 38.295 ml
5 mM 0.766 ml 3.83 ml 7.659 ml
10 mM 0.383 ml 1.915 ml 3.83 ml
50 mM 0.077 ml 0.383 ml 0.766 ml
注意: 部分产品我司仅能提供部分信息,我司不保证所提供信息的权威性,仅供客户参考交流研究之用。

参考文献

质检证书(COA)

如何获取质检证书(COA)?
请输入货号和一个与之匹配的批号。
例如:
批号:JS298415 货号:S20001-25g
在货品标签上如何找到货号和批号?

摩尔浓度计算器

质量 (mg) = 浓度 (mM) x 体积 (mL) x 分子摩尔量 (g/mol)

=
×
×