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ML-9盐酸盐

    
99.70%

ML-9 HYDROCHLORIDE

源叶(MedMol)
S89030 一键复制产品信息
105637-50-1
C15H18Cl2N2O2S
361.287
1-(5-氯萘-1-磺酰基)-1H-六氢-1,4-二吖庚因盐酸盐;1-(5-氯萘磺酰基)-1H-六氢-1,4-二氮杂卓, 盐酸盐;ML-9;ML-9 HYDROCHLORIDE;1-(5-CHLORONAPHTHALENE-1-SULFONYL)-1H-HEXAHYDRO-1,4-DIAZEPINE HCL;1-(5-CHLORONAPHTHALENE-1-SULFONYL)-1H
货号 规格 价格 上海 北京 珠海 重庆 武汉 购买数量
S89030-5mg促销
99.70%

¥119.00 ¥95.00

9 - - - -
S89030-25mg
99.70%

¥370.00

7 - - - -
S89030-100mg
≥98%

¥950.00

货期:2-3天 - - - -
产品介绍 参考文献 质检证书(COA) 摩尔浓度计算器 相关产品
产品描述: ML-9 is a selective and potent inhibitor of Akt kinase, inhibits myosin light-chain kinase (MLCK) and stromal interaction molecule 1 (STIM1) activity. ML-9 inhibits inhibits MLCK, PKA and PKC activity with Ki values of 4, 32 and 54 μM, respectively. ML-9 induces autophagy by stimulating autophagosome formation and inhibiting their degradation
靶点: Myosin;Myosin; Akt
参考文献: 1. Ito S, et al. ML-9, a myosin light chain kinase inhibitor, reduces intracellular Ca2+ concentration in guinea pig trachealis.Eur J Pharmacol. 2004 Feb 23;486(3):325-33. 2. Shaikh S, et al. The STIM1 inhibitor ML9 disrupts basal autophagy in cardiomyocytes by decreasing lysosome content.Toxicol In Vitro. 2018 Apr;48:121-127. 3. Kondratskyi A1, et al.Identification of ML-9 as a lysosomotropic agent targeting autophagy and cell death.Cell Death Dis. 2014 Apr 24;5:e1193.
溶解性: Soluble  in  DMSO、H2O
保存条件: 2-8℃
配置溶液浓度参考:
1mg 5mg 10mg
1 mM 2.768 ml 13.839 ml 27.679 ml
5 mM 0.554 ml 2.768 ml 5.536 ml
10 mM 0.277 ml 1.384 ml 2.768 ml
50 mM 0.055 ml 0.277 ml 0.554 ml
注意: 部分产品我司仅能提供部分信息,我司不保证所提供信息的权威性,仅供客户参考交流研究之用。

参考文献

质检证书(COA)

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摩尔浓度计算器

质量 (mg) = 浓度 (mM) x 体积 (mL) x 分子摩尔量 (g/mol)

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