货号	规格	价格	上海	北京	珠海	重庆	武汉
S89213-5mg	≥98%	￥300.00 S89213-5mg ￥300.00 3-5天	0 货期：3-5天	-	-	-	-
S89213-10mg	≥98%	￥497.00 S89213-10mg ￥497.00 3-5天	0 货期：3-5天	-	-	-	-
S89213-25mg	≥98%	￥1032.00 S89213-25mg ￥1032.00 3-5天	0 货期：3-5天	-	-	-	-
S89213-100mg	≥98%	￥2787.00 S89213-100mg ￥2787.00 3-5天	0 货期：3-5天	-	-	-	-

大包装询价收藏产品

加入购物车

到货通知，提交手机号入库后将短信通知。

产品描述：

SU4984 is a protein tyrosine kinase inhibitor, with an IC50 of 10-20 μM for fibroblast growth factor receptor 1 (FGFR1). SU4984 is also inhibits platelet-derived growth factor receptor, and insulin receptor. SU4984 can be used for the research of cancer

靶点：

FGFR1:10-20 μM (IC50);FGFR; IGF-1R; PDGFR

体外研究：

SU4984 (5-100 μM; 5 min) inhibits the kinase activity of FGFR1K with an IC50 of 10-20 μM in the presence of 1 mM adenosine triphosphate (ATP). SU4984 (10-90 μM; 5 min) inhibits the autophosphorylation of FGFR1 induced by aFGF in NIH 3T3 cells, with an IC50 of 20-40 μM. SU4984 (5 μM) substantially reduces tyrosine phosphorylation of the wild-type receptor and reduces 50% phosphorylation of constitutive C2 KIT. SU4984 (1-10 μM; 6 days) kills the C2 and P815 cells

参考文献：

1. Mohammadi M, et, al. Structures of the tyrosine kinase domain of fibroblast growth factor receptor in complex with inhibitors. Science. 1997 May 9;276(5314):955-60. 2. Ma Y, et, al. Indolinone derivatives inhibit constitutively activated KIT mutants and kill neoplastic mast cells. J Invest Dermatol. 2000 Feb;114(2):392-4.

溶解性：

Soluble in DMSO

保存条件：

-20℃

配置溶液浓度参考：

	1mg	5mg	10mg
1 mM	3 ml	14.998 ml	29.996 ml
5 mM	0.6 ml	3 ml	5.999 ml
10 mM	0.3 ml	1.5 ml	3 ml
50 mM	0.06 ml	0.3 ml	0.6 ml

注意：

部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。

参考文献

质检证书(COA)

输入产品批号：

如何获取质检证书(COA)?

请输入货号和一个与之匹配的批号。
例如:
批号：JS298415 货号：S20001-25g
在货品标签上如何找到货号和批号?

摩尔浓度计算器

质量 (mg) = 浓度 (mM) x 体积 (mL) x 分子摩尔量 (g/mol)

质量

浓度

体积

分子摩尔量

计算重置