首页
订购/客服:400-666-5481

ACH-000143

    
99.10%

ACH-000143

源叶(MedMol)
S89215 一键复制产品信息
2225836-30-4
C13H16ClN3O3
297.74
ACH-000143; ACH 000143; ACH000143;
货号 规格 价格 上海 北京 珠海 重庆 武汉 购买数量
S89215-5mg买3赠1
99.10%

¥640.00

5 - - - -
S89215-25mg促销
99.10%

¥1440.00 ¥1150.00

3 - - - -
S89215-100mg促销
99.10%

¥3840.00 ¥3070.00

3 - - - -
S89215-250mg促销
≥98%

¥8640.00 ¥6910.00

货期:2-3天 - - - -
产品介绍 参考文献 质检证书(COA) 摩尔浓度计算器 相关产品
产品描述: ACH-000143 have been identified as a novel agonist of the melatonin receptors MT1 and MT2
靶点: Melatonin Receptor; MT Receptor;MelatoninReceptor; MTReceptor
体外研究: ACH-000143 demonstrated subnanomolar potency at MT1/MT2 receptors, high oral bioavailability in rodents, peripherally preferred exposure, and excellent selectivity in a broad panel of targets.
体内研究: Two-month oral administration of ACH-000143 in high-fat diet rats led to a reduction in body weight gain similar to dapagliflozin with superior results on hepatic steatosis and triglyceride levels
参考文献: 1. Marcos Antonio Ferreira Jr, et al. Discovery of ACH-000143: A Novel Potent and Peripherally Preferred Melatonin Receptor Agonist that Reduces Liver Triglycerides and Steatosis in Diet-Induced Obese Rats. J Med Chem. 2021 Feb 25;64(4):1904-1929.
溶解性: Soluble  in  DMSO
保存条件: -20℃
配置溶液浓度参考:
1mg 5mg 10mg
1 mM 3.359 ml 16.793 ml 33.586 ml
5 mM 0.672 ml 3.359 ml 6.717 ml
10 mM 0.336 ml 1.679 ml 3.359 ml
50 mM 0.067 ml 0.336 ml 0.672 ml
注意: 部分产品我司仅能提供部分信息,我司不保证所提供信息的权威性,仅供客户参考交流研究之用。

参考文献

质检证书(COA)

如何获取质检证书(COA)?
请输入货号和一个与之匹配的批号。
例如:
批号:JS298415 货号:S20001-25g
在货品标签上如何找到货号和批号?

摩尔浓度计算器

质量 (mg) = 浓度 (mM) x 体积 (mL) x 分子摩尔量 (g/mol)

=
×
×