| 货号 | 规格 | 价格 | 上海 | 北京 | 珠海 | 重庆 | 武汉 | 购买数量 |
|---|---|---|---|---|---|---|---|---|
S89379-5mg |
≥98% | ￥2000.00 |
货期：3-5天 | - | - | - | - |
|
S89379-10mg |
≥98% | ￥3200.00 |
货期：3-5天 | - | - | - | - |
|
S89379-25mg |
≥98% | ￥5500.00 |
货期：3-5天 | - | - | - | - |
|
S89379-50mg |
≥98% | ￥9000.00 |
货期：3-5天 | - | - | - | - |
|
| 产品描述： | Xeruborbactam (QPX7728) is a potent, ultra-broad-spectrum boronic acid beta-lactamase inhibitor. Xeruborbactam inhibits key serine and metallo beta-lactamases at a nano molar range | ||||||||||||||||||||
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| 靶点： | Beta-lactamase | ||||||||||||||||||||
| 体外研究： | Xeruborbactam is a potent inhibitor of Class D carbapenemases from A. baumannii. Xeruborbactam is minimally affected by the activity of major MDR efflux pumps from P. aeruginosa, representing a significant improvement over the earlier generation boronate beta-lactamase inhibitor (BLI) vaborbactam. The ultra-broad-spectrum beta-lactamase inhibition profile combined with enhancement of the activity of multiple beta-lactam antibiotics with varying sensitivity to the intrinsic resistance mechanisms of efflux and permeability indicate Xeruborbactam is a useful inhibitor for use with multiple beta-lactam antibiotics. |
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| 参考文献： | 1. Lomovskaya O, et al, The Impact of Intrinsic Resistance Mechanisms on Potency of QPX7728, a New Ultra-Broad-Spectrum Beta-lactamase Inhibitor of Serine and Metallo Beta-Lactamases in Enterobacteriaceae, Pseudomonas aeruginosa, and Acinetobacter baumannii. Antimicrob Agents Chemother. 2020 Mar 30. pii: AAC.00552-20. | ||||||||||||||||||||
| 溶解性： | Soluble in DMSO | ||||||||||||||||||||
| 保存条件： | -20℃，避光 | ||||||||||||||||||||
| 配置溶液浓度参考： |
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| 注意： | 部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。 |
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