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三氮唑核苷

    
98%

Sodium 7-(methylthio)-3-nitro-4-oxo-4H-[1,2,4]triazolo[5,1-c][1,2,4]triazin-6-ide dihydrate

源叶(MedMol)
S89472 一键复制产品信息
928659-17-0
C5H7N6NaO5S
286.20
Riamilovir sodium hydrate; Riamilovir; Triazavirin; TZV;7-(甲硫基)-3-硝基-[1,2,4]三唑并[5,1-c][1,2,4]三嗪环-4(6H)-酮钠盐二水化合物;Triazavirin
货号 规格 价格 上海 北京 珠海 重庆 武汉 购买数量
S89472-5mg促销
98%

¥489.00 ¥390.00

货期:3-5天 - - - -
S89472-10mg促销
98%

¥880.00 ¥700.00

10 - - - -
S89472-50mg促销
98%

¥2650.00 ¥2120.00

5 - - - -
S89472-100mg促销
98%

¥3980.00 ¥3180.00

1 - - - -
产品介绍 参考文献 质检证书(COA) 摩尔浓度计算器 相关产品
产品描述: Triazavirin is a nucleoside analogue of nucleic acid and an antiviral agent. Triazavirin works by inhibiting the synthesis of viral RNA and DNA and replication of genomic fragments. Triazavirin is also an effective protective agent on the transmission stage of influenza
靶点: Nucleoside analogue; Influenza virus;NucleosideAntimetabolite/Analog; InfluenzaVirus; DNA/RNASynthesis
体外研究: The efficacy of Triazavirin against the tick-borne encephalitis virus is estimated in the sensitive cell culture. In a concentration of 128 mcg/mL Triazavirin is shown active in inhibition of the tick-borne encephalitis virus reproduction (strain Sofiin) by accumulation in the SKEV cell culture
体内研究: The therapeutic efficacy Triazavirin against experimental Forest-Spring encephalitis on albino mice is studied. The results shows that in high doses (200-400 mg/kg) Triazavirin moderately protects the infected animals. A significant increase of the animal lifespan in the test groups (from 4.1 to 4.8 days) and a statistically valid decrease of the virus accumulation in the target organ are observed
参考文献: 1. Kozhikhova KV, et al. Preparation of chitosan-coated liposomes as a novel carrier system for the antiviral drug Triazavirin. Pharm Dev Technol. 2018 Apr;23(4):334-342. 2. Loginova SIa, et al. Investigation of Triazavirin antiviral activity against tick-borne encephalitis pathogen in cell culture. Antibiot Khimioter. 2014;59(1-2):3-5. 3. Loginova SY, et al. Investigation of Therapeutic Efficacy of Triazavirin Against Experimental Forest-Spring Encephalitis on Albino Mice. Antibiot Khimioter. 2015;60(7-8):11-3.
溶解性: Soluble  in  DMSO、H2O
保存条件: -20℃
配置溶液浓度参考:
1mg 5mg 10mg
1 mM 3.494 ml 17.47 ml 34.941 ml
5 mM 0.699 ml 3.494 ml 6.988 ml
10 mM 0.349 ml 1.747 ml 3.494 ml
50 mM 0.07 ml 0.349 ml 0.699 ml
注意: 部分产品我司仅能提供部分信息,我司不保证所提供信息的权威性,仅供客户参考交流研究之用。

参考文献

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摩尔浓度计算器

质量 (mg) = 浓度 (mM) x 体积 (mL) x 分子摩尔量 (g/mol)

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