货号	规格	价格	上海	北京	珠海	重庆	武汉
S89514-5mg	≥98%	￥3490.00 S89514-5mg ￥3490.00 3-5天	0 货期：3-5天	-	-	-	-
S89514-10mg	≥98%	￥5890.00 S89514-10mg ￥5890.00 3-5天	0 货期：3-5天	-	-	-	-
S89514-25mg	≥98%	￥10500.00 S89514-25mg ￥10500.00 3-5天	0 货期：3-5天	-	-	-	-
S89514-100mg	≥98%	￥27500.00 S89514-100mg ￥27500.00 3-5天	0 货期：3-5天	-	-	-	-

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产品描述：

Cadrofloxacin (Caderofloxacin; CS-940), a orally active fluoroquinolone, is effective against aerobic/anaerobic Gram-positive and Gram-negative bacteria. Cadrofloxacin can be used for the research of infectious diseases

靶点：

Bacterial

体外研究：

Cadrofloxacin against M.tuberculosis with a MIC50 of 0.25 μg/mL.
Cadrofloxacin against Acinetobacter spp. and Stenotrophomonas (Xanthomonas) maltophilia with MIC90s of 0.03 and 2 μg/ml, respectively.
Cadrofloxacin against Haemophilus influenzae, Moraxella catarrhalis, and Neisseria spp. with MIC90s less than or equal to 0.06 μg/mL.
Cadrofloxacin against members of the family Enterobacteriaceae with MIC90s of 0.015 to 16 μg/mL (median MIC90, 0.06 μg/mL).

体内研究：

Cadrofloxacin (9 mg/kg; i.g.; once or twice daily for 14 consecutive days) increases the activity of hepatic CYP2E1 in rats Animal Model: Male Sprague-Dawley rats weighing 180-220 g Dosage: 9 mg/kg Administration: I.g. once or twice daily for 14 consecutive days Result: Enhanced the expression of hepatic CYP2E1 mRNA, inducing a 1.6-fold increase compared with that of control rats.The level of CYP2E1 protein in the hepatic microsomes was significantly higher than control group, 190% of that in control rats.

参考文献：

1. Biedenbach DJ, et al. Antimicrobial activity of CS-940, a new trifluorinated quinolone. Antimicrob Agents Chemother. 1995 Oct;39(10):2325-30.
2. Bryskier A, et al. Fluoroquinolones and tuberculosis. Expert Opin Investig Drugs. 2002 Feb;11(2):233-58.

溶解性：

Soluble in DMSO

保存条件：

-20℃

配置溶液浓度参考：

	1mg	5mg	10mg
1 mM	2.431 ml	12.154 ml	24.308 ml
5 mM	0.486 ml	2.431 ml	4.862 ml
10 mM	0.243 ml	1.215 ml	2.431 ml
50 mM	0.049 ml	0.243 ml	0.486 ml

注意：

部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。

参考文献

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摩尔浓度计算器

质量 (mg) = 浓度 (mM) x 体积 (mL) x 分子摩尔量 (g/mol)

质量

浓度

体积

分子摩尔量

计算重置

Cadrofloxacin

(S)-1-cyclopropyl-8-(difluoromethoxy)-6-fluoro-7-(3-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid

参考文献

质检证书(COA)

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摩尔浓度计算器

质量 (mg) = 浓度 (mM) x 体积 (mL) x 分子摩尔量 (g/mol)