货号	规格	价格	上海	北京	珠海	重庆	武汉
S89705-5mg买3赠1	99.90%	￥350.00 S89705-5mg ￥350.00 现货（买3赠1）	6 6	-	-	-	-
S89705-10mg买3赠1	99.90%	￥600.00 S89705-10mg ￥600.00 现货（买3赠1）	8 8	-	-	-	-
S89705-25mg促销	99.90%	￥1350.00 ￥1080.00 S89705-25mg ￥1080.00 现货	8 8	-	-	-	-
S89705-100mg促销	99.90%	￥3710.00 ￥2960.00 S89705-100mg ￥2960.00 现货	2 2	-	-	-	-

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产品描述：

Cetaben is a PPARα-independent peroxisome proliferator. Cetaben is a non-fibrate hypolipidemic agent and potently reduces the concentration of cholesterol and triglycerides

体外研究：

Cetaben (10 µM; 24 hours) induces severe micromorphological and ultrastructural changes in HepG2 and MH1C1 cells. After treatment with 100 µM cetaben, cells contained several Golgi regions, most of them disintegrated into vesicles.
Cetaben-treated (10 µM; 24 hours) cells were characterized by a striking heterogeneity of the peroxisomal population with the occurrence of dumbbell-shaped and cup-shaped peroxisomal profiles in MH1C1cells.

体内研究：

Cetaben reveales a significant rise in the activities of peroxisomal enzymes in both the liver and kidney at doses of 50-100 mg/kg body over 10 days, but the maximal effect is observed at 250 mg/kg. Animal Model: Male Wistar rats Dosage: 10,25,50,100,250 and 500 mg/kg Administration: Gavage; 10 day Result: Revealed a significant rise in the activities of peroxisomal enzymes in both the liver and kidney at doses of 50-100 mg/kg body over 10 days, but the maximal effect was observed at 250 mg/kg.

参考文献：

1. Chandoga J, et al. Cetaben and fibrates both influence the activities of peroxisomal enzymes in different ways. Biochem Pharmacol. 1994 Feb 9;47(3):515-9.

2. Kovacs W, et al. Cetaben-induced changes on the morphology and peroxisomal enzymes in MH1C1 rat hepatomacells and HepG2 human hepatoblastoma cells. Histochem Cell Biol. 2001 Jun;115(6):509-19.

溶解性：

soluble in DMSO

保存条件：

-20°C

配置溶液浓度参考：

	1mg	5mg	10mg
1 mM	2.766 ml	13.829 ml	27.658 ml
5 mM	0.553 ml	2.766 ml	5.532 ml
10 mM	0.277 ml	1.383 ml	2.766 ml
50 mM	0.055 ml	0.277 ml	0.553 ml

注意：

部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。

参考文献

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摩尔浓度计算器

质量 (mg) = 浓度 (mM) x 体积 (mL) x 分子摩尔量 (g/mol)

质量

浓度

体积

分子摩尔量

计算重置

西他苯

CETABEN

参考文献

质检证书(COA)

如何获取质检证书(COA)?

摩尔浓度计算器

质量 (mg) = 浓度 (mM) x 体积 (mL) x 分子摩尔量 (g/mol)