| 货号 | 规格 | 价格 | 上海 | 北京 | 珠海 | 重庆 | 武汉 | 购买数量 |
|---|---|---|---|---|---|---|---|---|
S89981-5mg |
≥98% | ￥460.00 |
5 | - | - | - | - |
|
S89981-10mg |
≥98% | ￥750.00 |
7 | - | - | - | - |
|
S89981-50mg |
≥98% | ￥2250.00 |
3 | - | - | - | - |
|
S89981-100mg |
≥98% | ￥3600.00 |
货期：2-3天 | - | - | - | - |
|
| 产品描述： | p-MPPI hydrochloride is a selective 5-HT1A receptor antagonist with high affinity for 5-HT1A receptors. p-MPPI hydrochloride can crosses the blood-brain barrier, and has clear antidepressant and anxiolytic-like effects | ||||||||||||||||||||
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| 靶点： | 5-HT1A Receptor;5-HTReceptor | ||||||||||||||||||||
| 体内研究： | p-MPPI hydrochloride (0.5-4.5 mg/kg; i.p.) shows anxiolytic-like profile in the murine elevated plus-maze. Animal Model: Adult male Swiss Webster mice (aged 8-9 weeks) Dosage: 0.5, 1.5, 4.5 mg/kg Administration: i.p. Result: Produced a significant and dose-related anxiolytic profile on both conventional (open arm avoidance) and ethological (risk assessment) measures. | ||||||||||||||||||||
| 参考文献： | 1. Sørensen E, et al. The selective 5-HT(1A) receptor antagonist p-MPPI antagonizes sleep--waking and behavioural effects of 8-OH-DPAT in rats. Behav Brain Res. 2001 Jun;121(1-2):181-7. 2. Cao BJ, et al. Anxiolytic-like profile of p-MPPI, a novel 5HT1A receptor antagonist, in the murine elevated plus-maze. Psychopharmacology (Berl). 1997 Feb;129(4):365-71. | ||||||||||||||||||||
| 溶解性： | Soluble in DMSO、H2O | ||||||||||||||||||||
| 保存条件： | -20℃ | ||||||||||||||||||||
| 配置溶液浓度参考： |
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| 注意： | 部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。 |
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