| 货号 | 规格 | 价格 | 上海 | 北京 | 珠海 | 重庆 | 武汉 | 购买数量 |
|---|---|---|---|---|---|---|---|---|
T14801-1mg促销 |
≥99%(HPLC) | ￥210.00 ￥189.00 |
8 | - | - | - | - |
|
T14801-5mg促销 |
≥99%(HPLC) | ￥875.00 ￥786.00 |
6 | - | - | - | - |
|
T14801-25mg促销 |
≥99%(HPLC) | ￥2960.00 ￥2660.00 |
3 | - | - | - | - |
|
T14801-100mg促销 |
≥99%(HPLC) | ￥8340.00 ￥7500.00 |
2 | - | - | - | - |
|
| 靶点： | AMPAR | ||||||||||||||||||||
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| 体内研究： | ZK200775 elevated the threshold for AMPA- and kainate-induced clonic seizures in mice with a THRD50 (threshold dose) of 2.9 (1.7–4.6) and 1.6 (1.3–2.0) mg/kg i.v., whereas the threshold for NMDA-induced seizures was elevated only in doses, THRD50 of 24.1 (21.9–26.5) mg/kg i.v., which affected motor coordination in the rotating rod, ED50 14.6 (12.1–17.6) mg/kg. ZK200775 in doses of 10 and 30 mg/kg i.v. reduced muscle tone in genetically spastic rats . ZK200775 (3.0 but not 1.5 or 6.0 mg/kg) significantly decreased the nicotine-induced (0.6 mg/kg) DA release in the NAcc and nicotine-stimulated LMA. ZK200775 (1.5, 3.0, 6.0 mg/kg) alone influenced neither DA release nor LMA. ZK200775 showed 34-fold selectivity for AMPA receptors compared to NMDA receptors and no affinity to nicotine receptors | ||||||||||||||||||||
| 溶解性： | DMSO: ≥20mg/mL | ||||||||||||||||||||
| 保存条件： | 2-8℃ | ||||||||||||||||||||
| 配置溶液浓度参考： |
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| 注意： | 部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。 |
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