| 货号 | 规格 | 价格 | 上海 | 北京 | 珠海 | 重庆 | 武汉 | 购买数量 |
|---|---|---|---|---|---|---|---|---|
T21518-1mg促销 |
≥98% | ￥390.00 ￥350.00 |
10 | - | - | - | - |
|
T21518-5mg促销 |
≥98% | ￥1280.00 ￥1150.00 |
10 | - | - | - | - |
|
T21518-10mg促销 |
≥98% | ￥2000.00 ￥1800.00 |
7 | - | - | - | - |
|
T21518-25mg促销 |
≥98% | ￥4400.00 ￥3960.00 |
3 | - | - | - | - |
|
T21518-50mg促销 |
≥98% | ￥7600.00 ￥6840.00 |
3 | - | - | - | - |
|
| 体内研究： | GSK2292767 exhibits high clearance (50 mL/min/kg) in vivo and low oral bioavailability (F < 2%) in a rat PK study. GSK2292767 (0.01-1 μM) has no e ect on QT interval, Tp e, or QRS and no signi cant risk of TdP arrhythmias in a rabbit cardiac ventricular wedge assay. GSK2292767 protects against eosinophil recruitment with an ED50 of 35 μg/kg in the brown Norway rat acute OVA model of Th2 driven in ammation in the lungs of rats. |
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| 参考文献： | 1. Down K, et, al. Optimization of Novel Indazoles as Highly Potent and Selective Inhibitors of Phosphoinositide 3-Kinase δ for the Treatment of Respiratory Disease. J Med Chem. 2015 Sep 24; 58(18): 7381-99. | ||||||||||||||||||||
| 保存条件： | -20℃ | ||||||||||||||||||||
| 配置溶液浓度参考： |
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| 注意： | 部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。 |
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