| 体内研究: |
Mean animal survivals of the ONO4057-treated animals significantly prolong to 21.0±4.4 days compare with 12.0±0.6 days in control group. Histological findings from grafts taken on day 7 show that severe focal cellular infiltration is observed in both groups, but the degree of hepatocyte necrosis in ONO4057-treated anmimals is milder than that in control group. |
| 参考文献: |
1. Kishikawa K, et al. ONO-4057, a novel, orally active leukotriene B4 antagonist: effects on LTB4-induced neutrophil functions. Prostaglandins. 1992 Oct;44(4):261-75. 2. Tanaka M, et al. Effect of leukotriene B(4) receptor antagonist (ONO4057) on hepatic allografting in rats. Transplant Proc. 2000 Nov;32(7):2340. |
| 保存条件: |
RT |
| 配置溶液浓度参考: |
|
1mg |
5mg |
10mg |
| 1 mM |
2.125 ml |
10.626 ml |
21.252 ml |
| 5 mM |
0.425 ml |
2.125 ml |
4.25 ml |
| 10 mM |
0.213 ml |
1.063 ml |
2.125 ml |
| 50 mM |
0.043 ml |
0.213 ml |
0.425 ml |
|
| 注意: |
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